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Structure and Properties of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-1 Isolated from Human Amniotic Fluid*
Insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) regulates the activity of the insulin-like growth factors in early pregnancy and is, thus, thought to play a key role at theExpand
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Identification of the amniotic fluid insulin‐like growth factor binding protein‐1 phosphorylation sites and propensity to proteolysis of the isoforms
Insulin‐like growth factor binding protein‐1 (IGFBP‐1) is the major secreted protein of human decidual cells during gestation and, as a modulator of insulin‐like growth factors or by independentExpand
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Proteomic analysis of exhaled breath condensate from single patients with pulmonary emphysema associated to alpha1-antitrypsin deficiency.
The non-invasive character of exhaled breath (EBC) collection makes this fluid attractive for monitoring the respiratory tract by the measurement of various compounds. Because EBC is likely toExpand
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Peroxidase catalyzed nitration of tryptophan derivatives. Mechanism, products and comparison with chemical nitrating agents.
The enzymatic nitration of tryptophan derivatives by oxidation of nitrite has been studied using lactoperoxidase and horseradish peroxidase, and compared with the chemical nitration produced byExpand
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Structural and biochemical characterization of a new type of lectin isolated from carp eggs.
A previously unidentified glycoprotein present in the eggs of the carp ( Cyprinus carpio ) was isolated and structurally characterized. The protein binds to a Sepharose 4B matrix and can be elutedExpand
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Analbuminemia in a Slovak Romany (gypsy) family: case report and mutational analysis.
BACKGROUND Analbuminemia is a rare autosomal recessive disorder manifested by the absence, or severe reduction, of circulating serum albumin. Here we report three new cases of hereditaryExpand
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Analbuminemia in a Swiss family is caused by a C --> T transition at nucleotide 4446 of the albumin gene.
OBJECTIVE To define the molecular defect that causes analbuminemia in an apparently healthy boy, son of non-consanguineous Swiss parents. DESIGN AND METHODS Total DNA, extracted from peripheralExpand
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Trypsin-based monolithic bioreactor coupled on-line with LC/MS/MS system for protein digestion and variant identification in standard solutions and serum samples.
The applicability of a trypsin-based monolithic bioreactor coupled on-line with LC/MS/MS for rapid proteolytic digestion and protein identification is here described. Dilute samples are passedExpand
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Human α-1-Microglobulin Is Covalently Bound to Kynurenine-derived Chromophores*
α-1-Microglobulin carries a set of covalently linked chromophores that give it a peculiar yellow-brown color, fluorescence properties, and both charge and size heterogeneity. In this report it isExpand
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Formation of reactive nitrogen species at biologic heme centers: a potential mechanism of nitric oxide-dependent toxicity.
The peroxidase-catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide has been studied in detail using the enzymes lactoperoxidase (LPO) from bovine milk and horseradishExpand
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