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Gabapentin (neurontin) and S‐(+)‐3‐isobutylgaba represent a novel class of selective antihyperalgesic agents
1 Gabapentin (neurontin) is a novel antiepileptic agent that binds to the α2δ subunit of voltage‐dependent calcium channels. The only other compound known to possess affinity for this recognitionExpand
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Evidence for an involvement of the brain cholecystokinin B receptor in anxiety.
The effect of neuropeptide cholecystokinin (CCK) receptor agonists and antagonists was examined in the rat elevated X-maze model of anxiety. The selective CCK-B receptor antagonists CI-988 (PDExpand
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Comparison of venous and capillary blood sampling for the clinical determination of tobramycin serum concentrations.
Tobramycin concentrations have been determined in serum from capillary, venous and arterial blood samples taken from 16 patients during and after surgery. In 73 paired samples the concentrations inExpand
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Modified enzyme immunoassays for tobramycin using reduced sample and reagent volumes.
The accuracy of two modified enzyme immunoassay (EMIT) methods using reduced sample and reagent volumes for determining serum tobramycin concentrations was compared with that of the standard method.Expand
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Evidence foraninvolvement ofthebrain cholecystokinin B receptor inanxiety
ABSTRACT The effect of neuropeptide cholecystokinin(CCK)receptor agonists andantagonists wasexaminedintherat elevated X-maze model of anxiety. The selective CCK-Breceptor antagonists CI-988 (PDExpand
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