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Semisynthesis and in vitro anticancer activities of andrographolide analogues.
The plant Andrographis paniculata found throughout Southeast Asia contains Andrographolide 1, a diterpenoid lactone, which has antitumour activities against in vitro and in vivo breast cancer models.… Expand
Evaluation of antioxidant and nitric oxide inhibitory activities of selected Malaysian medicinal plants.
Methanol extracts of seven Malaysian medicinal plants were screened for antioxidant and nitric oxide inhibitory activities. Antioxidant activity was measured by using FTC, TBA and DPPH free radical… Expand
Cytotoxic caged-polyprenylated xanthonoids and a xanthone from Garcinia cantleyana.
Phytochemical studies on the leaves and trunk bark of Garcinia cantleyana yielded five caged-xanthonoids including one tetra- and four tri-prenylated xanthones, cantleyanone A (1),… Expand
*Semisynthesis and cytotoxic activities of andrographolide analogues
- S. Jada, A. S. Hamzah, N. Lajis, M. S. Saad, M. Stevens, J. Stanslas
- Chemistry, Medicine
- Journal of enzyme inhibition and medicinal…
- 1 January 2006
Andrographolide 1, a diterpenoid lactone of the plant Andrographis paniculata, known to possess antitumour activity in in vitro and in vivo breast cancer models was subjected to semisynthesis leading… Expand
Malaysianol A, a new trimer resveratrol oligomer from the stem bark of Dryobalanops aromatica.
A new resveratrol trimer, malaysianol A (1), five known resveratrol oligomers: laevifonol (2), ampelopsin E (3), α-viniferin (4), ε-viniferin (5), diptoindonesin A (6), and bergenin (7) have been… Expand
A MEHPPV/VOPcPhO composite based diode as a photodetector
Abstract We demonstrate a solution-processed visible wavelength photodetector using an organic semiconductor blend of poly[2-methoxy-5-(2′-ethylhexyloxy)-p-phenylene vinylene] (MEHPPV) and vanadyl… Expand
Isolation and cytotoxicity of triterpenes from the roots of Phyllanthus pulcher Wall. ex Müll. Arg. (Euphorbiaceae)
The dried powdered roots of Phyllanthus pulcher Wall. ex Mull. Arg. (Euphorbiaceae), were sequentially extracted with dichloromethane (DCM), ethyl acetate (EtOAc) and methanol (MeOH). The extracts… Expand
Isolation, Characterization and Biological Activities of Chemical Constituents of Ophiorrhiza and Hedyotis Species
- A. S. Hamzah
Chemical investigation on the leaves of Ophiorrhiza species, O. communis and O. tomentosa, has resulted in the isolation of two indole type alkaloids, harman and strictosidinic acid. … Expand
Synthesis of 2,3-Dioxo-5-(substituted)arylpyrroles and Their 2-Oxo-5-aryl-3-hydrazone Pyrrolidine Derivatives
Some novel 2,3-dioxo-5-(substituted)arylpyrroles have been synthesized. Among these, pyrrolidine compound 1b was converted to 2,3-dioxo-5-aryl pyrrolidine 2b. Finally a set of hydrazone derivatives… Expand
Kaempferitrin from the leaves of Hedyotis verticillata and its biological activity.