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Using Serum Creatinine To Estimate Glomerular Filtration Rate: Accuracy in Good Health and in Chronic Kidney Disease
Context Experts increasingly use the Modification of Diet in Renal Disease (MDRD) equation to estimate glomerular filtration rate (GFR). Contribution This cross-sectional study compared GFR estimatedExpand
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Measured and estimated GFR in healthy potential kidney donors.
BACKGROUND Nonradiolabeled iothalamate clearance is an accurate way to determine glomerular filtration rate (GFR). Objectives of this study are to define the normal range of nonradiolabeledExpand
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Glomerular filtration rate estimated by cystatin C among different clinical presentations.
Glomerular filtration rate (GFR) estimates from serum creatinine has not been generalizable across all populations. Cystatin C has been proposed as an alternative marker for estimating GFR. TheExpand
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An estimated glomerular filtration rate equation for the full age spectrum.
BACKGROUND Glomerular filtration rate (GFR) is accepted as the best indicator of kidney function and is commonly estimated from serum creatinine (SCr)-based equations. Separate equations have beenExpand
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Kidney stones and the risk for chronic kidney disease.
BACKGROUND AND OBJECTIVES Kidney stones lead to chronic kidney disease (CKD) in people with rare hereditary disorders (e.g., primary hyperoxaluria, cystinuria), but it is unknown whether kidneyExpand
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The Substantial Loss of Nephrons in Healthy Human Kidneys with Aging.
Nephron number may be an important determinant of kidney health but has been difficult to study in living humans. We evaluated 1638 living kidney donors at Mayo Clinic (MN and AZ sites) and ClevelandExpand
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Relative performance of the MDRD and CKD-EPI equations for estimating glomerular filtration rate among patients with varied clinical presentations.
BACKGROUND The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation was developed using both CKD and non-CKD patients to potentially replace the Modification of Diet in Renal DiseaseExpand
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The implications of anatomical and functional changes of the aging kidney: with an emphasis on the glomeruli.
Aging is both a natural and inevitable biological process. With advancing age, the kidneys undergo anatomical and physiological changes that are not only the consequences of normal organ senescenceExpand
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Kidney Transplant Function and Histological Clearance of Virus Following Diagnosis of Polyomavirus‐Associated Nephropathy (PVAN)
Polyomavirus‐associated nephropathy (PVAN) is managed by reduced immunosuppression with or without antiviral therapy. Data from 55 patients with biopsy‐proven PVAN were analyzed for adverse outcomesExpand
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The Association Between Age and Nephrosclerosis on Renal Biopsy Among Healthy Adults
BACKGROUND Chronic kidney disease is common with older age and is characterized on renal biopsy by global glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis. OBJECTIVEExpand
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