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Nuttingins A-F and malonganenones D-H, tetraprenylated alkaloids from the Tanzanian gorgonian Euplexaura nuttingi.
Six new tetraprenylated purine alkaloids, designated nuttingins A-F (1-6), were isolated together with three known malonganenones, A-C (12-14), and five new closely related malonganenones, D-HExpand
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Amino acid derivatives from the marine sponge Jaspis digonoxea.
Six heterocycles, bengamide A [1], bengamide B [2], cyclo(L-trans-(4-hydroxyprolinyl)-L-phenylalanine) [4], the functionalized nonene lactone 5, the novel digonazole [6] andExpand
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Mode of inhibition of HIV-1 reverse transcriptase by polyacetylenetriol, a novel inhibitor of RNA- and DNA-directed DNA polymerases.
Polyacetylenetriol (PAT), a natural marine product from the Mediterranean sea sponge Petrosia sp., was found to be a novel general potent inhibitor of DNA polymerases. It inhibits equally well theExpand
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Didmolamide A and B, two new cyclic hexapeptides from the marine ascidian Didemnum molle.
Two novel cyclic hexapeptides, didmolamides A and B, were isolated from the compound ascidian Didemnum molle collected in Madagascar. The structure of the two peptides was elucidated byExpand
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Njaoamines G and H, two new cytotoxic polycyclic alkaloids and a tetrahydroquinolone from the marine sponge Neopetrosia sp.
Abstract Two new polycyclic alkaloids, njaoamines G ( 1 ) and H ( 2 ) and 1,2,3,4-tetrahydroquinolin-4-one ( 3 ) have been isolated from the sponge Neopetrosia sp. collected at Pemba Island,Expand
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New avarone and avarol derivatives from the marine sponge Dysidea cinerea.
Six new avarol and avarone derivatives, 3'-hydroxyavarone [3], 3',6'-dihydroxyavarone [4], 6'-hydroxyavarol [5], 6'-acetoxyavarol [6], 6'-acetoxyavarone [7], and 6'-hydroxy-4'-methoxyavarone [8], areExpand
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Three new sesquiterpene hydroquinones from marine origin
Abstract Three new sesquiterpene hydroquinones peyssonol A and B (5 and 6 and hyatellaquinone (7) have been isolated from the alga Peyssonnelia sp. and the sponge Hyatella intestinalis. The structureExpand
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Clathsterol, a novel anti-HIV-1 RT sulfated sterol from the sponge Clathria species.
As part of a search for novel inhibitors of humandeficiency virus type 1 (HIV-1) reverse transcriptase (RT), the MeOH-EtOAc extract of a Red Sea sponge, Clathria sp., was shown to be active.Expand
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The biomimetic synthesis of marine alkaloid related pyrido- and pyrrolo[2,3,4-kl]acridines
Abstract A biomimetic reaction between β,β′-diamenoketones (e.g. kynuramine, kynurenine or o,o′-diaminobenzophenone) and a variety cyclohexanediones and quinones leading to pyrido[2,3,4-kl) acridinesExpand
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Callynormine A, a new marine cyclic peptide of a novel class.
[structure: see text] A novel cyclic peptide, callynormine A, was isolated from the Kenyan marine sponge Callyspongia abnormis and its structure elucidated by interpretation of its NMR data and X-rayExpand
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