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Medication compliance and persistence: terminology and definitions.
OBJECTIVE The aim of the study is to provide guidance regarding the meaning and use of the terms "compliance" and "persistence" as they relate to the study of medication use. METHODS A literature… Expand
A Retrospective Chart Review to Assess Burden of Illness Among Patients with Severe Aplastic Anemia with Insufficient Response to Immunosuppressive Therapy
Background: Aplastic anemia (AA) is a rare disease, with an incidence of 1-2 new cases per million per year in Europe and North America. Primary therapies for AA for patients who do not have a… Expand
A framework for planning and critiquing medication compliance and persistence research using prospective study designs.
BACKGROUND Medication compliance and persistence are important determinants of clinical outcomes. With the application of evidence-based therapy, it is increasingly important to ensure that studies… Expand
Patient-reported Depression Severity Measured by the PHQ-9 and Impact on Work Productivity: Results From a Survey of Full-time Employees in the United States
- G. Jain, A. Roy, V. Harikrishnan, S. Yu, O. Dabbous, C. Lawrence
- Journal of occupational and environmental…
- 1 March 2013
Objective: To examine the burden of depression on work productivity. Methods: Full-time employees with diagnosed depression were surveyed using the Patient Health Questionnaire for depression… Expand
Association between severity of depression and self-perceived cognitive difficulties among full-time employees.
- C. Lawrence, A. Roy, V. Harikrishnan, S. Yu, O. Dabbous
- The primary care companion for CNS disorders
- 30 May 2013
OBJECTIVE To assess the relationship between self-perceived deficits in cognition and severity of depression reported by individuals in full-time employment. METHOD Individuals ≥ 18 years of age… Expand
Patient-Reported Health-Related Quality of Life Improves over Time in Patients with Chronic Immune Thrombocytopenia Receiving Long-Term Treatment with Eltrombopag
Background: EXTEND (June 2006 to July 2015) was an open-label, dose-adjustment extension study to evaluate the safety and efficacy of eltrombopag for the treatment of patients with chronic immune… Expand
Patient Reported Health-related Quality of Life in Co-morbid Insomnia: Results from a Survey of Primary Care Patients in the United States
Background: This study attempts to establish the incremental burden of co-morbid Insomnia in an indigent and underserved population among patients with other primary Chronic diagnoses. Methods: Adult… Expand
Health Care Resource Use (HCRU) Due To Bleeding Related Episodes (BRE) In Patients With Immune Thrombocytopenic Purpura (ITP) Receiving Eltrombopag (EPAG), Romiplostim (ROMI), Or Rituximab (RITUX):…
Health‐related quality of life in children with chronic immune thrombocytopenia treated with eltrombopag in the PETIT study
- J. Grainger, V. Blanchette, Kelly M. Grotzinger, A. Roy, J. Bussel
- British journal of haematology
- 1 April 2019
The PETIT (Eltrombopag in Pediatric Patients with Thrombocytopenia from Chronic ITP) trial showed that in children aged 1–17 years with chronic or persistent immune thrombocytopenia (ITP),… Expand
Panobinostat Plus Bortezomib Versus Lenalidomide in Patients with Relapsed and/or Refractory Multiple Myeloma: A Matching-Adjusted Indirect Treatment Comparison of Survival Outcomes using…
- I. Majer, G. Wetering, Z. Polányi, Arun Krishna, E. Gray, A. Roy
- Applied Health Economics and Health Policy
- 1 February 2017
BackgroundIn the UK, the standard of care for patients with multiple myeloma who received ≥2 prior treatments is lenalidomide plus dexamethasone (LEN + DEX) and pomalidomide plus DEX (POM + DEX) (in… Expand