• Publications
  • Influence
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system.
TLDR
The hypothesis that alpha-Syn is an essential presynaptic, activity-dependent negative regulator of DA neurotransmission is supported. Expand
The frequency of significant pathology in women attending a general gynaecological service for postcoital bleeding
TLDR
To determine whether negative cervical cytology excludes serious pathology in women with postcoital bleeding and to determine whether post coital bleeding increases the risk of serious pathologyIn women with an abnormal smear. Expand
Ovarian cancer screening.
TLDR
The investigators use the World Health Organization criteria for a screening program as a framework for discussing current issues in ovarian cancer screening, including screening modalities and strategies, high- and low-risk populations, and the acceptability, psychological impact, and cost of screening. Expand
High frequency of loss of heterozygosity in vulval intraepithelial neoplasia (VIN) is associated with invasive vulval squamous cell carcinoma (VSCC)
TLDR
The data suggest that genetic instability in VIN, reflected by LOH, may increase the risk of invasion and molecular events differ in HPV‐positive and ‐negative VSCC and 3p25 may be the site of a tumor suppressor gene involved in HPV-independent vulval carcinogenesis. Expand
A comparison of national cancer registry and direct follow-up in the ascertainment of ovarian cancer
TLDR
The National Health Service Central Register and direct follow-up were used to document ovarian and fallopian tube cancers in 22 000 women from 1986 to 1993 and NHSCR ascertainment was incomplete and direct following-up provided additional information. Expand
Fibroid embolisation: a technique not without significant complications
  • A. Rosenthal
  • Medicine
  • BJOG : an international journal of obstetrics and…
  • 1 March 2001
TLDR
It may be prudent not to perform uterine artery embolisation in older multiparous women, or those with arterial disease, to avoid the potentially fatal sequelae illustrated by this case. Expand
PREVALENCE SCREENING FOR OVARIAN CANCER USING RISK OF OVARIAN CANCER ALGORITHM
TLDR
Genes identified in the present work may elucidate regulatory mechanisms of cervical cell proliferation causing a pathological phenotype in cervical epithelium and suggest additional factors and mutational events may be important in the pathogenesis of invasive carcinoma of the uterine cervix. Expand
Breast cancer metastasising to the pelvis and abdomen: what the gynaecologist needs to know
Please cite this paper as: Moore EK, Roylance R, Rosenthal AN. Breast cancer metastasising to the pelvis and abdomen: what the gynaecologist needs to know. BJOG 2012;119:788–794.
Final results of 4-monthly screening in the UK Familial Ovarian Cancer Screening Study (UKFOCSS Phase 2).
TLDR
The final results of 4-monthly screening in one of the largest such trials worldwide are reported, with results likely to provide greater benefits to women at high-risk of Ovarian/Fallopian tube cancer. Expand
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