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Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.
Two classes of sequences in the yeast Saccharomyces cerevisiae are subject to transcriptional silencing: the silent mating-type cassettes and telomeres. In this report we demonstrate that theExpand
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Promoter-Proximal Introns in Arabidopsis thaliana Are Enriched in Dispersed Signals that Elevate Gene Expression[W][OA]
Introns that elevate mRNA accumulation have been found in a wide range of eukaryotes. However, not all introns affect gene expression, and direct testing is currently the only way to identifyExpand
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Intron-mediated regulation of gene expression.
  • A. Rose
  • Biology, Medicine
  • Current topics in microbiology and immunology
  • 2008
Introns can significantly affect gene expression in plants and many other eukaryotes in a variety of ways. Several types of gene regulation, both positive and negative, that involve plant introns areExpand
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Comparative and functional analysis of intron-mediated enhancement signals reveals conserved features among plants
Introns in a wide range of organisms including plants, animals and fungi are able to increase the expression of the gene that they are contained in. This process of intron-mediated enhancement (IME)Expand
  • 117
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Requirements for intron-mediated enhancement of gene expression in Arabidopsis.
  • A. Rose
  • Biology, Medicine
  • RNA
  • 1 November 2002
To explore possible mechanisms of intron-mediated enhancement of gene expression, the features of PAT1 intron 1 required to elevate mRNA accumulation were systematically tested in transgenicExpand
  • 113
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Introns act post-transcriptionally to increase expression of the Arabidopsis thaliana tryptophan pathway gene PAT1.
  • A. Rose, R. Last
  • Biology, Medicine
  • The Plant journal : for cell and molecular…
  • 1 March 1997
The expression of the Arabidopsis thaliana PAT1 gene, which encodes the tryptophan biosynthetic enzyme phosphoribosylanthranilate transferase, was investigated using translational fusions of the PAT1Expand
  • 126
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The enduring mystery of intron-mediated enhancement.
  • J. Gallegos, A. Rose
  • Biology, Medicine
  • Plant science : an international journal of…
  • 1 August 2015
Within two years of their discovery in 1977, introns were found to have a positive effect on gene expression. Numerous examples of stimulatory introns have been described since then in very diverseExpand
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The effect of intron location on intron-mediated enhancement of gene expression in Arabidopsis.
  • A. Rose
  • Biology, Medicine
  • The Plant journal : for cell and molecular…
  • 1 December 2004
Introns are often required for full expression of genes in organisms as diverse as plants, insects, nematodes, yeast, and mammals. To explore the potential mechanisms of intron-mediated enhancementExpand
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Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring
Objective: To investigate the occurrence of status epilepticus and seizure clusters, and the duration until first seizure at epilepsy monitoring units in the United States. Methods: The authorsExpand
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