• Publications
  • Influence
The arrangement of the three cone classes in the living human eye
Adaptive optics and retinal densitometry are combined to obtain the first images of the arrangement of S, M and L cones in the living human eye, allowing the sharpest images ever taken of the living retina. Expand
Adaptive optics scanning laser ophthalmoscopy.
The first scanning laser ophthalmoscope that uses adaptive optics to measure and correct the high order aberrations of the human eye is presented, permitting axial sectioning of retinal tissue in vivo. Expand
A population study on changes in wave aberrations with accommodation.
A typical eye will benefit over the entire accommodative range (0-6 D) if aberrations are corrected for distance viewing, even at high accommodative levels. Expand
Functional consequences of the relative numbers of L and M cones.
This study examines the functional consequences of variation in the relative numbers of L and M cones (L/M cone ratio) for two observers whose ratios were measured by direct imaging and indicates that neural factors play an important role in stabilizing unique yellow against variation inThe L/M cones ratio. Expand
Automated identification of cone photoreceptors in adaptive optics retinal images.
  • K. Li, A. Roorda
  • Computer Science, Medicine
  • Journal of the Optical Society of America. A…
  • 1 May 2007
Voronoi analysis of large montages of AO retinal images confirmed the general hexagonal-packing structure of retinal cones as well as the general cone density variability across portions of the retina. Expand
Packing arrangement of the three cone classes in primate retina
A detailed analysis of the spatial arrangement of L, M and S cones in the living eyes of two humans and one monkey using statistical methods that characterize the arrangement of each type of cone in the mosaic of photoreceptors. Expand
High-resolution imaging with adaptive optics in patients with inherited retinal degeneration.
The authors present the first report of cone structure in vivo in patients with mutations in rhodopsin and RPGR-ORF15 and show that macular cones display distinct characteristics, depending on the underlying disease. Expand
Revealing Henle's fiber layer using spectral domain optical coherence tomography.
Recognition of the optical properties of HFL can explain reflectivity changes imaged in this layer in association with macular pathology, and a novel method to distinguish HFL from true ONL is demonstrated. Expand
Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment.
AOSLO images provided a sensitive measure of disease progression and treatment response in patients with inherited retinal degenerations, and larger studies of cone structure using high-resolution imaging techniques are urgently needed to evaluate the effect of CNTF treatment. Expand
Disruption of the retinal parafoveal capillary network in type 2 diabetes before the onset of diabetic retinopathy.
It is established that AV channels are disrupted in type 2 diabetes, even before the onset of diabetic retinopathy, with a novel application of AOSLO imaging, which is possible to visualize parafoveal capillaries and identify AV channels noninvasively. Expand