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Activity of compounds isolated from Chilean lichens against experimental cutaneous leishmaniasis.
Community Participation in Chagas Disease Vector Surveillance: Systematic Review
TLDR
Results confirm that professional, insecticide-based vector control is highly effective, but also show that reinfestation by native triatomines is common and widespread across Latin America.
Comparative evaluation of pyrethroid insecticide formulations against Triatoma infestans (Klug): residual efficacy on four substrates.
TLDR
WP formulations were not as effective as SC flowable formulations but, overall in the longer term, WP gave grater mortality rates of T. infestans nymphs exposed at up to six months post-spraying.
First Report of Colonies of Sylvatic Triatoma infestans (Hemiptera: Reduviidae) in the Paraguayan Chaco, Using a Trained Dog
TLDR
A new approach to detecting sylvatic Triatominae is presented, using a trained dog, which has successfully confirmed sylvatics populations of T. infestans and other triatomine species in Paraguay.
Wing geometry in Triatoma infestans (Klug) and T. melanosoma Martinez, Olmedo & Carcavallo (Hemiptera: Reduviidae)
TLDR
Geometric morphometrics is used to examine geographical and interspecific variation in the Triatoma infestans complex, vectors of Chagas disease in southern Latin America, using six landmarks defining the membranous part of the hemelytra to analyse the geographical patterns of variation.
In vivo efficacy of oral and intralesional administration of 2-substituted quinolines in experimental treatment of new world cutaneous leishmaniasis caused by Leishmania amazonensis
TLDR
It is suggested that chimanine B may be chosen as a lead molecule in the development of oral therapy against leishmaniasis.
Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase.
TLDR
Kinetic analyses suggested the BBIQ alkaloids are mixed inhibitors of TR; the best TR inhibitor, cepharanthine, had an IC50 of 15 microM, which is in the same order of magnitude as its LC50 against T. cruzi.
Efficacy of Orally Administered 2-Substituted Quinolines in Experimental Murine Cutaneous and Visceral Leishmaniases
TLDR
From the present study, quinoline 5 is the most promising compound against both cutaneous and visceral leishmaniasis.
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