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Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation.
Although stimulation of adrenergic nerves or adrenal chromaffin cells causes the release of catecholamines, in many cases it does not cause a decrease in the catecholamine content of these cells. OneExpand
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Arachidonic acid mediates muscarinic inhibition and enhancement of N-type Ca2+ current in sympathetic neurons
  • L. Liu, A. Rittenhouse
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 20 December 2002
N-type Ca2+ channels participate in acute activity-dependent processes such as regulation of Ca2+-activated K+ channels and in more prolonged events such as gene transcription and long-termExpand
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Ca2+ influx through both L‐ and N‐type Ca2+ channels increases c‐fos expression by electrical stimulation of sympathetic neurons
During direct membrane depolarization, Ca2+ influx primarily through L‐type Ca2+ (L‐) channels initiates activity‐dependent gene transcription. This is surprising given that in most neurons aExpand
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The Antifungal Imidazole Clotrimazole and its Major In Vivo Metabolite are Potent Blockers of the Calcium-Activated Potassium Channel in Murine Erythroleukemia Cells
Abstract. Clotrimazole (CLT), a member of the antifungal imidazole family of compounds, has been found to inhibit both calcium (Ca2+)-activated 86Rb and potassium (K) fluxes of human red cells and toExpand
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M1 Muscarinic Receptors Inhibit L-type Ca2+ Current and M-Current by Divergent Signal Transduction Cascades
Ion channels reside in a sea of phospholipids. During normal fluctuations in membrane potential and periods of modulation, lipids that directly associate with channel proteins influence gating byExpand
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Neurotransmitter modulation of calcium channels in rat sympathetic neurons
Adrenergic, cholinergic, and a variety of peptide neurotransmitters are known to modulate Ca currents in peripheral neurons. Using a protocol that allows for simultaneous assessment of effects onExpand
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Regulation of voltage-gated Ca2+ channels by lipids.
Great skepticism has surrounded the question of whether modulation of voltage-gated Ca(2+) channels (VGCCs) by the polyunsaturated free fatty acid arachidonic acid (AA) has any physiological basis.Expand
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Modulation of N-Type Calcium Channel Activity by G-Proteins and Protein Kinase C
N-type voltage-gated calcium channel activity in rat superior cervical ganglion neurons is modulated by a variety of pathways. Activation of heterotrimeric G-proteins reduces whole-cell currentExpand
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Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons.
We recently reported that arachidonic acid (AA) inhibits L- and N-type Ca(2+) currents at positive test potentials in the presence of the dihydropyridine L-type Ca(2+) channel agonist (+)-202-791 inExpand
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The Ca2+ channel β subunit determines whether stimulation of Gq-coupled receptors enhances or inhibits N current
In superior cervical ganglion (SCG) neurons, stimulation of M1 receptors (M1Rs) produces a distinct pattern of modulation of N-type calcium (N-) channel activity, enhancing currents elicited withExpand
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