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A Validated Whole-Genome Association Study of Efficient Food Conversion in Cattle
The genetic factors that contribute to efficient food conversion are largely unknown. Several physiological systems are likely to be important, including basal metabolic rate, the generation of ATP,Expand
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Combining partial correlation and an information theory approach to the reversed engineering of gene co-expression networks
TLDR
MOTIVATION We present PCIT, an algorithm for the reconstruction of gene co-expression networks (GCN) that combines the concept partial correlation coefficient with information theory to identify significant gene to gene associations defining edges in the reconstruction. Expand
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Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection
BackgroundMastitis in dairy cattle results from infection of mammary tissue by a range of micro-organisms but principally coliform bacteria and Gram positive bacteria such as Staphylococcus aureus.Expand
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Gastrointestinal nematode challenge induces some conserved gene expression changes in the gut mucosa of genetically resistant sheep.
Sheep have a varying ability to resist infection with gastrointestinal nematodes. This ability is due in part to genetic differences that exist between individuals. In order to define theseExpand
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Accuracy of prediction of genomic breeding values for residual feed intake and carcass and meat quality traits in Bos taurus, Bos indicus, and composite beef cattle.
The aim of this study was to assess the accuracy of genomic predictions for 19 traits including feed efficiency, growth, and carcass and meat quality traits in beef cattle. The 10,181 cattle in ourExpand
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Gene expression patterns during intramuscular fat development in cattle.
Deposition of intramuscular fat, or "marbling," in beef cattle contributes significantly to meat quality variables, including juiciness, flavor, and tenderness. The accumulation of intramuscular fatExpand
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Genetic and phenotypic characterisation of animal, carcass, and meat quality traits from temperate and tropically adapted beef breeds. 3. Meat quality traits
Abstract. Meat quality measures, including objective measures of tenderness (shear force and compression), were taken on 2 muscles (M. longissimus thoracis et lumborum (LTL) and M. semitendinosusExpand
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Linkage disequilibrium over short physical distances measured in sheep using a high-density SNP chip.
The extent of linkage disequilibrium (LD) between genetic loci has implications for both association studies and the accuracy of genomic prediction. To characterise the persistence of LD in diverseExpand
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Association weight matrix for the genetic dissection of puberty in beef cattle
We describe a systems biology approach for the genetic dissection of complex traits based on applying gene network theory to the results from genome-wide associations. The associations ofExpand
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A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle
Polymorphisms that affect complex traits or quantitative trait loci (QTL) often affect multiple traits. We describe two novel methods (1) for finding single nucleotide polymorphisms (SNPs)Expand
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