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Cytokine-associated emotional and cognitive disturbances in humans.
BACKGROUND Infectious, autoimmune, and neurodegenerative diseases are associated with profound psychological disturbances. Studies in animals clearly demonstrate that cytokines mediateExpand
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Combining dimensional and categorical representation of psychosis: the way forward for DSM-V and ICD-11?
BACKGROUND There is good evidence that psychotic symptoms segregate into symptom dimensions. However, it is still unclear how these dimensions are associated with risk indicators and other clinicalExpand
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The 20-Year Longitudinal Trajectories of Social Functioning in Individuals With Psychotic Disorders.
OBJECTIVE Social impairment is a long-recognized core feature of schizophrenia and is common in other psychotic disorders. Still, to date the long-term trajectories of social impairment in psychoticExpand
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Autism risk following antidepressant medication during pregnancy
Background. Previous studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have beenExpand
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Validity and Stability of Performance-Based Estimates of Premorbid Educational Functioning in Older Patients with Schizophrenia
This paper presents the results of two studies of the validity of word-recognition reading as an indicator of premorbid functioning in schizophrenia. The first examined the stability over a 6-yearExpand
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Working Memory Performance in Poor Outcome Schizophrenia: Relationship to Age and Executive Functioning
Performance on the Letter-Number Sequencing (LNS) and Wisconsin Card Sorting Tests (WCST) have been shown to be significantly correlated in patients with schizophrenia, a relationship postulated toExpand
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New insights into the link between cardiovascular disease and depression. Commentary
Introduction: Although the association between depression and cardiovascular disease (CVD) is well documented, the underlying mechanisms for this relationship remain unclear. In this paper, weExpand
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Computational challenges in modeling maternal effects in psychiatric disorders
The goal of this thesis is to explore, improve and implement some advanced modern computational methods in statistics, focusing on applications in genetics. The thesis has three majorExpand