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Automutilation induced by clonidine in mice.
Clonidine (2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, St155, Catapres), after administration of a single large dose, was found to induce automutilation in mice housed individually inExpand
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Possible involvement of a central noradrenergic system in automutilation induced by clonidine in mice.
Automutilation induced by a single large dose of clonidine was potentiated by pretreatment with methamphetamine, caffeine and theophyline, while it was inhibited by acute administration of reserpine,Expand
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Cardiovascular changes induced by large doses of clonidine in mice.
Clonidine at doses of 0.5-1.0 mg/kg i.p. produced an initial rise followed by a sustained fall in blood pressure. The initial pressor response became more marked and the onset of hypotensive effectExpand
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