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Distribution of Determinants for Symptom Production and Host Range on the Three RNA Components of Cucumber Mosaic Virus
Summary Eighteen pseudorecombinants were constructed in vitro by exchanging the three genomic RNA segments between pairs of three strains of cucumber mosaic virus (CMV). Inoculation of the CMV… Expand
Molecular Studies on Bromovirus Capsid Protein VI. Contributions of the N-Terminal Arginine-Rich Motif of BMV Capsid Protein to Virion Stability and RNA Packaging
Abstract Specific interactions are likely to occur between the highly conserved N-proximal arginine-rich motif (ARM) of Brome mosaic virus (BMV) coat protein (CP) and each of three genomic RNAs and a… Expand
Optical nano-constructs composed of genome-depleted brome mosaic virus doped with a near infrared chromophore for potential biomedical applications.
We have engineered an optical nanoconstruct composed of genome-depleted brome mosaic virus doped with indocyanine green (ICG), an FDA-approved near-infrared (NIR) chromophore. Constructs are highly… Expand
Molecular Studies on Bromovirus Capsid Protein: V. Evidence for the Specificity of Brome Mosaic Virus Encapsidation Using RNA3 Chimera of Brome Mosaic and Cucumber Mosaic Viruses Expressing…
Abstract Brome mosaic bromovirus (BMV) and cucumber mosaic cucumovirus (CMV) are structurally and genetically very similar. The specificity of the BMV and CMV coat proteins (CPs) during in vivo… Expand
Virus-mimicking nano-constructs as a contrast agent for near infrared photoacoustic imaging.
- S. Gupta, M. Chatni, A. Rao, V. Vullev, L. Wang, B. Anvari
- Materials Science, Medicine
- 15 February 2013
We report the first proof-of-principle demonstration of photoacoustic imaging using a contrast agent composed of a plant virus protein shell, which encapsulates indocyanine green (ICG), the only… Expand
Viral RNAs Are Unusually Compact
A majority of viruses are composed of long single-stranded genomic RNA molecules encapsulated by protein shells with diameters of just a few tens of nanometers. We examine the extent to which these… Expand
Functional analysis of the N-terminal basic motif of a eukaryotic satellite RNA virus capsid protein in replication and packaging
- Venkatesh Sivanandam, D. Mathews, R. Garmann, Gonca Erdemci-Tandogan, R. Zandi, A. Rao
- Biology, Chemistry
- Scientific reports
- 19 May 2016
Efficient replication and assembly of virus particles are integral to the establishment of infection. In addition to the primary role of the capsid protein (CP) in encapsidating the RNA progeny,… Expand
Requirement fora Viral trans-Acting FactorEncodedbyBrome MosaicVirusRNA-2Provides Strong Selection InVivo forFunctional Recombinants
Interaction ofspecific nucleotide sequenceswithtrans-acting proteins isintrinsic toreplication ofviral aswell aseucaryotic genomes.Bromemosaic virus RNA-2encodes oneofthetwoviral proteins… Expand
Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells.
Previously we had shown that allospecific bulk cultures of cytolytic T lymphocytes lysed the products of cloned class I major histocompatibility genes expressed after DNA-mediated gene transfer. In… Expand