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Gut microbial composition in patients with psoriasis
TLDR
The study of the gut microbiome and enterotype shows from the first time a specific “psoriatic core intestinal microbiome” that clearly differs from the one present in healthy population. Expand
Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidants.
TLDR
The administration under medical advice of synergistic combinations of some of the above mentioned antioxidants in the diet as well as topically (for skin protection) may have favorable effects on the health and quality of life of women, especially of those who cannot be treated with HR, suffer high levels of oxygen stress. Expand
Low concentrations of curcumin induce growth arrest and apoptosis in skin keratinocytes only in combination with UVA or visible light.
TLDR
A new therapeutic concept for the treatment of hyperproliferative diseases by combining topical curcumin with UVA or visible light is suggested, which avoids the use of carcinogenic irradiation that is part of regular phototherapy. Expand
Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial
TLDR
The mixture of probiotics was effective in reducing SCORAD index and reducing the use of topical steroids in patients with moderate atopic dermatitis in a 12-week randomized, double-blind, placebo-controlled intervention trial. Expand
α-MSH is expressed in cultured human melanocytes and keratinocytes
TLDR
The data provide strong evidence for the production of POMC-peptides - especially α-MSH - in keratinocytes and melanocytes and has to be seen in the context of the skin immune system. Expand
An hydroalcoholic extract of Curcuma longa lowers the apo B/apo A ratio Implications for atherogenesis prevention
TLDR
This and recent data on the increased anti-atherogenic action of the physiological antioxidant tocopherol in the presence of phenolic co-antioxidants (which eliminate the tocopheroxyl radical), justifies planned clinical research to test the usefulness of the curcuma extract as a co-anioxidant complement to standard treatments to prevent or retard atherosclerosis. Expand
The mechanism of melanocyte dendrite formation: the impact of differentiating keratinocytes.
TLDR
In the present study different culture systems were tested in order to observe the mechanism of melanocyte dendrite formation, and the role of keratinocytes in this process was focused on. Expand
Measurement of anti-inflammatory effects of glucocorticoids on human keratinocytes in vitro. Comparison of normal human keratinocytes with the keratinocyte cell line HaCaT.
TLDR
The thymidine incorporation rate of the cells was not affected by the glucocorticoids indicating that the observed suppression of cytokine induction was not the result of a generalised cell damage, and the possible use of the generally available HaCaT cells for the pharmacological testing of anti-inflammatory activities in vitro. Expand
Curcumin in combination with visible light inhibits tumor growth in a xenograft tumor model
TLDR
The present findings suggest a combination of curcumin and light as a new therapeutic concept to increase the efficacy ofCurcumin in the treatment of cancer. Expand
Case series of familial frontal fibrosing alopecia and a review of the literature
TLDR
Early diagnosis in premenopausal stage is frequent in case series and allows us to begin the protocol treatment in the first stage of the disease, but long‐term progression will remain uncertain until a definitive treatment could be established by multicenter randomized controlled trials. Expand
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