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Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
TLDR
The results suggest that centrally administered NK1 and NK2 receptor agonists and antagonists can modulate anxiety, as evaluated in the elevated plus-maze test in mice. Expand
Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice
TLDR
Results indicate that tachykinin receptor antagonists, acting through NK1, NK2 and NK3 receptors, produce powerful antinociception when injected i.c.d. or by i.p., suggesting a distinct mechanism of action. Expand
Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice
TLDR
It is shown that meloxicam dose-dependently exhibited systemic antinociceptive action when assessed against neurogenic and inflammatory pain caused by acetic acid, formalin and capsaicin models. Expand
Chemical and pharmacological examination of antinociceptive constituents of Wedelia paludosa.
TLDR
It was found that fractions as well as kaurenoic acid and luteolin exhibit marked antinociceptive action in mice using acetic acid-induced writhing, more active than some well-known analgesic drugs, such as acetyl salicylic acid, acetaminophen, dipyrone and indomethacin. Expand
Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action.
TLDR
It is concluded that dipyrone produces peripheral, spinal and supraspinal antinociception when assessed on formalin and capsaicin-induced pain as well as in glutamate-induced hyperalgesia in mice. Expand
A 3-O-methylated mannogalactan from Pleurotus pulmonarius: structure and antinociceptive effect.
TLDR
A mannogalactan was tested for its effects on the acetic acid-induced writhing reaction in mice, a typical model for inflammatory pain, causing a marked and dose-dependent inhibition of the nociceptive response, and an inflammatory response was not inhibited. Expand
Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus.
TLDR
Data extend previous studies and indicate that the two ellagitannins isolated from P.sellowianus, identified as furosin and geraniin are, at least in part, responsible for the antinociceptive actions reported previously for the hydroalcoholic extract of P. sellowianu and other plants belonging to the genus Phyllanthus. Expand
Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice.
TLDR
Findings suggest that stigmasterol and beta-sitosterol may account, at least in part, for the antinociceptive actions reported previously for the hydroalcoholic extract of Phyllanthus corcovadensis. Expand
Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action.
TLDR
DPHD produces dose-dependent and pronounced systemic, spinal, and supraspinal antinociception in mice, including against the neurogenic nocICEption induced by formalin and capsaicin. Expand
Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae).
TLDR
Results of the present study extend previous data and indicate that all extracts of Phyllanthus plants so far studied exhibit pronounced antinociceptive when assessed in chemical models of nociception, namely acetic acid-induced writhing, and formalin and capsaicin-induced licking. Expand
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