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Mesencephalic Trigeminal Nucleus Development Is Dependent on Krox-20 Expression
- Shampa De, A. Q. Nguyen, C. Shuler, Jack E. Turman Jr.
- Medicine, BiologyDevelopmental Neuroscience
- 1 February 2005
It is shown that Krox-20 null mutants have twice as many Me5 neurons relative to wildtypes at E15, but by birth have half the number of Me5 cells as wildtypes, and TUNEL studies reveal a period of increased apoptosis from E17-P0 in mutants.