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Antioxidant activity applying an improved ABTS radical cation decolorization assay.
The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition
Fruit and vegetables rich in anthocyanins demonstrated the highest antioxidant activities, followed by those rich in flavanones and flavonols, while the hydroxycinnamate-rich fruit consistently elicited the lower antioxidant activities.
Interaction between flavonoids and the blood–brain barrier: in vitro studies
- K. Youdim, M. Dobbie, G. Kuhnle, A. Proteggente, N. Abbott, C. Rice-Evans
- BiologyJournal of Neurochemistry
- 1 April 2003
It is demonstrated that flavonoids and some metabolites are able to traverse the blood–brain barrier (BBB) and that the potential for permeation is consistent with compound lipophilicity.
A controlled investigation of the cause of chronic idiopathic axonal polyneuropathy.
A logistic regression analysis identified environmental toxin exposure and hypertriglyceridaemia, but not glucose intolerance or alcohol overuse as significant risk factors that deserve further investigation as possible causes of CIAP.
Potential problems of ascorbate and iron supplementation: pro-oxidant effect in vivo?
- A. Proteggente, A. Rehman, B. Halliwell, C. Rice-Evans
- Chemistry, MedicineBiochemical and biophysical research…
- 2 November 2000
No compelling evidence for a pro-oxidant effect of ascorbate supplementation, in the presence or absence of iron, on DNA base damage was observed and a significant decrease occurred in levels of 8-oxo-7,8-dihydroguanine by ascorBate supplementation and 5-hydroxymethyl uracil by both ascor Bate plus iron supplementation.
Gender Differences in Steady-state Levels of Oxidative Damage to DNA in Healthy Individuals
- A. Proteggente, T. England, A. Rehman, C. Rice-Evans, B. Halliwell
- BiologyFree radical research
- 1 January 2002
The role of gender in predisposition to oxidative damage to DNA needs to be addressed in future studies and the results are discussed in relation to the Vitamin C and iron status of the subjects and to the existing, yet limited, literature data.
Hesperetin Glucuronide, a Photoprotective Agent Arising from Flavonoid Metabolism in Human Skin Fibroblasts¶
The results indicate that hesperetin glucuronides, but not he Speretin, protect against UV-A-induced necrotic cell death.
Iron supplementation and oxidative damage to DNA in healthy individuals with high plasma ascorbate.
- A. Proteggente, T. England, C. Rice-Evans, B. Halliwell
- MedicineBiochemical and biophysical research…
- 19 October 2001
There were no detrimental effects, over the period under investigation, in terms of oxidative damage to DNA, and the effects of larger doses or of longer supplementation periods should also be investigated.
The Compositional Characterisation and Antioxidant Activity of Fresh Juices from Sicilian Sweet Orange (Citrus sinensis L. Osbeck) Varieties
- A. Proteggente, A. Saija, A. De Pasquale, C. Rice-Evans
- Chemistry, MedicineFree radical research
- 1 June 2003
Orange juices, particularly those rich in anthocyanins, may represent a significant dietary source of flavonoids, and a comparison of the phenolic compositions, the ascorbic acid contents and the antioxidant activities of fresh Sicilian orange juices showed a good correlation with the determined antioxidant capacity.
Physiological Factors Influencing Vitamin E Biokinetics
- J. Lodge, W. Hall, Y. Jeanes, A. Proteggente
- Chemistry, MedicineAnnals of the New York Academy of Sciences
- 1 December 2004
Data show that several physiological factors influence the uptake of newly absorbed α‐tocopherol, and that this is an important consideration in the design of future vitamin E supplementation studies.