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High-resolution fMRI of Content-sensitive Subsequent Memory Responses in Human Medial Temporal Lobe
TLDR
The present data suggest a gradient of content sensitivity from posterior (parahippocampal) to anterior (perirhinal) MTL cortex, with MTL cortical regions differentially contributing to successful encoding based on event content.
Learning-related representational changes reveal dissociable integration and separation signatures in the hippocampus and prefrontal cortex
TLDR
High-resolution functional magnetic resonance imaging in humans is used to examine how representations of memory elements change to either differentiate or generalize across related events and highlights how memory elements are represented to simultaneously promote generalization across memories and protect from interference.
Hippocampal contribution to the novel use of relational information in declarative memory
TLDR
Selective hippocampal activation in humans during recognition of pairs of items whose relationship was not explicitly learned but could be mediated through an overlapping relation with an explicitly learned common item suggests a specific role for the human hippocampus in the novel expression of declarative memories.
The hippocampus and inferential reasoning: building memories to navigate future decisions
TLDR
This review considers different perspectives on the role of the hippocampus in successful inferential reasoning during both memory encoding and retrieval as well as prospective theories of hippocampal function that suggest memories are actively constructed to anticipate future decisions and actions.
Content representation in the human medial temporal lobe.
TLDR
Findings indicate differential contributions of MTL subregions to event representation via a distributed code along the anterior-posterior axis of M TL that depends on the nature of event content.
Flexible Memories: Differential Roles for Medial Temporal Lobe and Prefrontal Cortex in Cross-Episode Binding
TLDR
These results demonstrate distinct encoding and retrieval mechanisms that support mnemonic flexibility, revealing a unique role for MTL regions in cross-episode binding during encoding and engagement of interactive MTL-PFC processes during flexible transfer at test.
Dissociation between explicit memory and configural memory in the human medial temporal lobe.
TLDR
Findings in functional magnetic resonance imaging indicate dissociable roles for hippocampus in learning that supports explicit recognition and for anterior MTL cortex in configural learning and converge with studies of amnesia.
Functional heterogeneity in posterior parietal cortex across attention and episodic memory retrieval.
TLDR
The present functional parcellation of PPC indicates that 2 additional mechanisms (mediated by latIPS and AnG) positively track retrieval outcomes, further suggesting that SPL activation during retrieval reflects top-down attention.
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