A. Prange

Publications333
h-index70
Citations17,195
Highly Influential Citations210
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Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism.
TLDR
In patients with hypothyroidism, partial substitution of triiodothyronine for thyroxine may improve mood and neuropsychological function; this finding suggests a specific effect of the triiod Timothyronine normally secreted by the thyroid gland.
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Oxytocin induces maternal behavior in virgin female rats.
TLDR
It is suggested that the release of oxytocin and prostaglandin F2 alpha during labor may promote maternal behavior in rats and this behavior persisted and its incidence was dose-related.
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Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity.
TLDR
Data are consistent with the postulate that this treatment with DALA activates the mesolimbic DA system, as microinjection of the peptidase-resistant enkephalin analog produced a dose-dependent increase in locomotion and rearing which was antagonized by neuroleptic administration in the nucleus accumbens.
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Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat
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Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin.
  • C. Pedersen, A. Prange
  • Biology, Psychology
    Proceedings of the National Academy of Sciences…
  • 1 December 1979
TLDR
Elevated or recently elevated levels of estrogen may be necessary for the induction of full maternal behavior by oxytocin, functions related to parturition and nuturing in virgin female rats.
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The Thyrotropin-Releasing Hormone (TRH) Hypothesis of Homeostatic Regulation: Implications for TRH-Based Therapeutics
TLDR
It is proposed that the main neurobiological function of TRH is to promote homeostasis, accomplished through neuronal mechanisms resident in these four integrated systems that together comprise a general TRH homeostatic system.
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Oxytocin potently enhances novelty-induced grooming behavior in the rat
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Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for graves’ disease
TLDR
Preliminary findings in a small group of patients with Graves’ disease are consistent with earlier findings that thyroid replacement with T4-T3 combination improves mental functioning.
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Interactions between "handling" and acrylamide on endocrine responses in rats.
TLDR
Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and thatHad been exposed to 100 mg/kg acrylamide and found Prolactin levels were significantly lower in acRYlamide-exposed nonhandled animals.
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Neurotensin blocks certain amphetamine-induced behaviours
TLDR
Since NT and dopamine are present in substantial quantities in the nucleus accumbens, NT may act in the amygdala to modulate dopaminergic function and HA does not produce neuroleptic-like effects when injected into nucleus caudatus, the observed effects of NT in AM-treated rats were probably not due to impaired motor function.
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