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Non-hormonal post-coital contraceptive action of neem oil in rats.
Since the post-coital contraceptive effect of neemOil seems to be non-hormonal, neem oil would be expected to elicit less side effects than the steroidal contraceptives. Expand
Anti-implantation activity of some indigenous plants in rats.
Various extracts of one hundred and eight medicinal plants were screened for their anti-implantation activity in female albino rats and a few plants were either inactive or showed insignificant antifertility activity. Expand
Effect of sub-acute oral cyanide administration in rats: protective efficacy of alpha-ketoglutarate and sodium thiosulfate.
A promising role is indicated of alpha-KG and STS for the treatment of prolonged cyanide exposures in female rats following oral administration of 7.0 mg/kg (0.5 LD50) and concomitant use of both interventions afforded to maximum protection. Expand
Potentialities of Some Indigenous Plants for Antifertility Activity
AbstractThirty extracts of twenty medicinal plants have been screened for their anti-implantation activity in female rats. 50% ethanolic and methanolic extracts of Pueraria tuberosa DC (tubers)Expand
Antifertility profile of the aqueous extract of Moringa oleifera roots.
The antifertility effect of the extract appears to be due to multiple attributes, including estrogenic, anti-estrogenic, progestational and antiprogestational activities. Expand
Dose Dependent Effects on Lymphoid Organs following a Single Dermal Application of Sulphur Mustard in Mice
Changes in body weight, organ/body weight ratio, haematology, histology and cellularity of spleen and thymus and degenerative histological changes show that a single sublethal dermal dose of SM can cause considerable dose dependent systemic effects in Balb/c mice. Expand
Antifertility investigations on embelin -- an oral contraceptive of plant origin. Part I -- Biological properties.
  • A. Prakash
  • Biology, Medicine
  • Planta medica
  • 1 March 1981
Embelin (embelic acid; 2,5-dihydroxy-3-undecyl-1,4-benzoquinone), a potent oral contraceptive of plant origin, has been investigated for its biological properties and exhibited significant antiestrogenic and progestational properties. Expand
Contraceptive potency of Pueraria tuberosa D.C. and its hormonal status.
The observations suggest that tubers of P. C. tuberosa D.C. possess significant antifertility activity, whereas hexane, chloroform, methanol, petroleum ether and benzene extracts are significantly effective to prevent implantation only in rats and mice. Expand
Short term toxicity of embelin in female rats
The toxicity of emblin has been assessed in female cyclic rats. Its administration at a dose of 120 mg/kg body weight did not cause any changes in the weight of liver, kidney and spleen, however, theExpand