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Validation of pharmacy records in drug exposure assessment.
The completeness of medication histories in hospital medical records of patients admitted to general internal medicine wards.
- H. S. Lau, C. Florax, A. Porsius, A. de Boer
- Medicine, Political ScienceBritish journal of clinical pharmacology
- 1 June 2000
The medication history in the hospital medical record is often incomplete, as 25% of the prescription drugs in use is not recorded and 61% of all patients has one of more drugs not registered.
Abstracts of papers
The mechanism, resulting in a constant drug delivery from the system, may be summarized as follows: the surface of the relatively poor-penetrated and drug containing restraining phase in the interior of the device, is exposed to the extraction liquids with a time dependent rate and contributes to the release process from the megaloporous system.
Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme
Reducing prescribing of highly anticholinergic antidepressants for elderly people: randomised trial of group versus individual academic detailing
- M. V. van Eijk, J. Avorn, A. Porsius, A. de Boer
- Medicine, PsychologyBMJ : British Medical Journal
- 17 March 2001
Both the individual and the group visits decreased the use of highly anticholinergic antidepressants and increased the use in elderly people and these approaches are practical means to improve prescribing by continuing medical education.
Evaluation of antiparkinsonian drugs in pharmacy records as a marker for Parkinson's disease
Based on the high PPV of the predictive model, antiparkinsonian drugs can be used as a reliable marker for PD in pharmacy records, and pharmacy records cannot be used to estimate prevalence of PD.
Undertreatment of hypercholesterolaemia: a population-based study.
- A. Mantel‐Teeuwisse, W. Verschuren, A. de Boer
- MedicineBritish journal of clinical pharmacology
- 1 April 2003
Over 95% of the population eligible for the pharmacological treatment of hypercholesterolaemia was either untreated or was uncontrolled, and to decrease undertreatment, identification of high-risk patients should be increased.
Drug-Induced Lipid Changes
- A. Mantel‐Teeuwisse, Judith M.E. Kloosterman, A. M. Zee, O. Klungel, A. Porsius, A. Boer
- Medicine, BiologyDrug safety
Adverse or beneficial effects on serum cholesterol levels do not always translate into a higher or lower, respectively, incidence of cardiovascular disease, because these drugs may influence cardiovascular risk through multiple pathways.
Comparison of different methods to estimate prevalence of drug use by using pharmacy records.
Modulation of Adrenoceptor‐Mediated Cardiovascular Effects by Short‐Term In Vivo Infusion of Isoproterenol in Rats
- W. Vleeming, H. V. van Rooij, J. Werner, A. Porsius
- Biology, MedicineJournal of cardiovascular pharmacology
- 1 October 1990
It is concluded that in the pathogenesis of heart failure the β-adrenoceptor-mediated effects of catecholamines are attenuated and α-adreneceptor- mediated effects become progressively important.