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NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS
Glial progenitor cells of the developing CNS committed to the oligodendrocyte lineage (OPCs) express the chondroitin sulfate proteoglycan, NG2. A proportion of OPCs fail to differentiate past theExpand
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NG2‐expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system
The mammalian adult central nervous system (CNS) is known to respond rapidly to demyelinating insults by regenerating oligodendrocytes for remyelination from a dividing precursor population. AExpand
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Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis.
Saltatory conduction in the nervous system is enabled through the intimate association between the leading edge of the myelin sheath and the axonal membrane to demarcate the node of Ranvier. The 186Expand
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The response of NG2-expressing oligodendrocyte progenitors to demyelination in MOG-EAE and MS
Remyelination of primary demyelinated lesions is a common feature of experimental models of multiple sclerosis (MS) and is also suggested to be the normal response to demyelination during the earlyExpand
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4: NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult CNS
Glial progenitor cells identified by expression of the NG2 chondroitin sulphate proteoglycan comprise an abundant cell population in both white and grey matter of the mature rodent CNS, 3–10% of theExpand