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Human Dental pulp stem cells (hDPSCs): isolation, enrichment and comparative differentiation of two sub-populations
TLDR
This study characterized and compared two subpopulations of adult stem cells derived from human dental pulp, and suggested that STRO-1+/c-Kit+/CD34− hDPSCs and STROs might represent two distinct stem cell populations, with different properties.
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Human Serum Promotes Osteogenic Differentiation of Human Dental Pulp Stem Cells In Vitro and In Vivo
TLDR
It is demonstrated that human serum (HS) is a suitable alternative to FCS, indeed its addition to culture medium induces a high hDPSCs proliferation rate and improves the in vitro osteogenic differentiation.
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Human dental pulp stem cells expressing STRO‐1, c‐kit and CD34 markers in peripheral nerve regeneration
TLDR
It is demonstrated that STRO‐1+/c‐Kit+/CD34+ hDPSCs, associated with neural crest derivation, represent a promising source of stem cells for the treatment of demyelinating disorders and might provide a valid alternative tool for future clinical applications to achieve functional recovery after injury or peripheral neuropathies besides minimizing ethical issues.
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Neural crest derived stem cells from dental pulp and tooth-associated stem cells for peripheral nerve regeneration
TLDR
The literature concerning the application of tooth derived stem cell populations combined with different conduits to peripheral nerve injuries animal models is reviewed, highlighting their regenerative contribution exerted through either glial differentiation and neuroprotective/neurotrophic effects on the host tissue.
View on Wolters Kluwer
Fibroin scaffold repairs critical-size bone defects in vivo supported by human amniotic fluid and dental pulp stem cells.
TLDR
The findings demonstrated the strong potential of stem cells/fibroin bioengineered constructs for correcting large cranial defects in animal model and is likely a promising approach for the reconstruction of human large skeletal defects in craniofacial surgery.
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Human amniotic fluid-derived and dental pulp-derived stem cells seeded into collagen scaffold repair critical-size bone defects promoting vascularization
TLDR
These data confirmed the strong potential of bioengineered constructs of stem cell–collagen scaffold for correcting large cranial defects in an animal model and highlighting the role of stem cells in neovascularization during skeletal defect reconstruction.
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Stem cells isolated from human dental pulp and amniotic fluid improve skeletal muscle histopathology in mdx/SCID mice
TLDR
This study shows that hAFSCs and hDPSCs represent potential sources of stem cells for translational strategies to improve the histopathology and potentially alleviate the muscle weakness in patients with DMD.
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In vitro differentiation into insulin-producing β-cells of stem cells isolated from human amniotic fluid and dental pulp.
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Use of a 3D Floating Sphere Culture System to Maintain the Neural Crest-Related Properties of Human Dental Pulp Stem Cells
TLDR
3D sphere culture provides a favorable micro-environment for neural crest-derived hDPSCs to preserve their biological properties and is demonstrated to be a favorable environment for osteogenic and myogenic commitments.
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Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard Phacoemulsification Surgery
TLDR
Comparative evaluation of morphological features of anterior capsules and apoptosis induction in epithelial cells after femtosecond laser-assisted cataract surgery (FLACS) and standard phacoemulsification surgery revealed a significant mean best-corrected visual acuity (BCVA) improvement 3 months after surgery, and no major intraoperative nor postoperative complications occurred.
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