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Non-invasive low-intensity pulsed ultrasound accelerates bone healing in the rabbit.
The effect of ultrasound (US) on the rate of fibula osteotomy healing in 139 mature New Zealand white rabbits was assessed in this study. Bilateral midshaft fibular osteotomies were made using a 1-mmExpand
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Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery.
BACKGROUND The initial development of pulsed electromagnetic field (PEMF) therapy and its evolution over the last century for use in clinical surgery has been slow, primarily because of lack ofExpand
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A pulsing electric field (PEF) increases human chondrocyte proliferation through a transduction pathway involving nitric oxide signaling
A potential treatment modality for joint pain due to cartilage degradation is electromagnetic fields (EMF) that can be delivered, noninvasively, to chondrocytes buried within cartilage. A pulsed EMFExpand
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Augmentation of Bone Repair by Inductively Coupled Electromagnetic Fields
Pulsing electromagnetic fields of low frequency and strength have been inductively coupled across skin, directly to bone, to enhance the repair of canine osteotomies. The induced voltage field inExpand
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Nonthermal electromagnetic fields: From first messenger to therapeutic applications
  • A. Pilla
  • Medicine
  • Electromagnetic biology and medicine
  • 15 May 2013
Nonthermal pulsed electromagnetic fields, from low frequency to pulse-modulated radio frequency, have been successfully employed as adjunctive therapy for the treatment of delayed and non-unionExpand
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Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems.
  • A. Pilla
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 28 September 2012
This study shows that a non-thermal pulse-modulated RF signal (PRF), configured to modulate calmodulin (CaM) activation via acceleration of Ca(2+) binding kinetics, produced an immediate nearlyExpand
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  • A. Pilla
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • 1 October 1974
A variety of in vivo studies have established that it is possible to influence biologic growth and repair processes by an artificial change in the electrical and/or magnetic environment of the siteExpand
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Electromagnetic fields as first messenger in biological signaling: Application to calmodulin-dependent signaling in tissue repair.
BACKGROUND The transduction mechanism for non-thermal electromagnetic field (EMF) bioeffects has not been fully elucidated. This study proposes that an EMF can act as a first messenger in theExpand
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