A Human Genome Diversity Cell Line Panel
A resource of 1064 cultured lymphoblastoid cell lines (LCLs) () from individuals in different world populations and corresponding milligram quantities of DNA is deposited at the Foundation Jean…
Y chromosome sequence variation and the history of human populations
Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting…
The History and Geography of Human Genes: Abridged paperback Edition
Synthetic maps of human gene frequencies in Europeans.
Synthetic maps constructed for Europe and the Near East show clines in remarkable agreement with those expected on the basis of the spread of early farming in Europe, supporting the hypothesis that this spread was a demic spread rather than a cultural diffusion of farming technology.
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
SNPs at nine loci were reproducibly associated with myocardial infarction, but tests of common and rare CNVs failed to identify additional associations with my Cardiovascular Infarction risk.
Reconstruction of human evolution: bringing together genetic, archaeological, and linguistic data.
- L. Cavalli-Sforza, A. Piazza, P. Menozzi, J. Mountain
- BiologyProceedings of the National Academy of Sciences…
- 1 August 1988
The reconstruction of human evolutionary history was checked with statistical techniques such as "boot-strapping" and changes some earlier conclusions and is in agreement with more recent ones, including published and unpublished DNA-marker results.
The History and Geography of Human Genes. Princeton, NJ (Princeton University Press) 1994.
DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case‐control study
It is suggested that bladder‐cancer risk can be genetically modulated by XRCC3, which may repair DNA cross‐link lesions produced by aromatic amines and other environmental chemicals.
XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects.
All the analysed polymorphisms could result in deficient DNA repair and suggest a need for further investigation into the possible interactions between these polymorphisms, smoking and other risk factors.
Mitochondrial DNA variation of modern Tuscans supports the near eastern origin of Etruscans.
Interpopulation comparisons reveal that the modern population of Murlo, a small town of Etruscan origin, is characterized by an unusually high frequency (17.5%) of Near Eastern mtDNA haplogroups, supporting a direct and rather recent genetic input from the Near East--a scenario in agreement with the Lydian origin of ETruscans.