• Publications
  • Influence
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis.
Multiple sclerosis is increasingly being recognized as a neurodegenerative disease that is triggered by inflammatory attack of the CNS. As yet there is no satisfactory treatment. Using experimentalExpand
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Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis
Optical coherence tomography (OCT) is a new method that could aid analysis of neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre layer (RNFL). Meta-analysesExpand
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Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss
  • A. Petzold
  • Medicine
  • Journal of the Neurological Sciences
  • 15 June 2005
This review on the role of neurofilaments as surrogate markers for axonal degeneration in neurological diseases provides a brief background to protein synthesis, assembly, function and degeneration.Expand
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Neurofilaments as biomarkers in neurological disorders
Neuroaxonal damage is the pathological substrate of permanent disability in various neurological disorders. Reliable quantification and longitudinal follow-up of such damage are important forExpand
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The utility of cerebrospinal fluid analysis in patients with multiple sclerosis
Diagnosis of multiple sclerosis (MS) requires the exclusion of other possible diagnoses. For this reason, the cerebrospinal fluid (CSF) should be routinely analysed in patients with a first clinicalExpand
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The investigation of acute optic neuritis: a review and proposed protocol
Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple sclerosis (MS) at some point during their disease course. Differentiation of acute episodes ofExpand
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Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis
BACKGROUND Structural retinal imaging biomarkers are important for early recognition and monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction of spectralExpand
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Distribution of retinal layer atrophy in patients with Parkinson disease and association with disease severity and duration.
WITH GREAT INTEREST WE READ THE RECENT ARTICLE BY Garcia-Martin and associates. In this article, the authors suggested that in Parkinson disease (PD) ‘‘a reduction of retinal ganglion cells may leadExpand
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Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases
Objective Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into cerebrospinal fluid hasExpand
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Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis
Background Neuromyelitis optica (NMO) and relapsing-remitting multiple sclerosis (RRMS) are difficult to differentiate solely on clinical grounds. Optical coherence tomography (OCT) studiesExpand
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