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Electrical synapses and their functional interactions with chemical synapses
  • A. Pereda
  • Medicine, Biology
  • Nature Reviews Neuroscience
  • 1 April 2014
Brain function relies on the ability of neurons to communicate with each other. Interneuronal communication primarily takes place at synapses, where information from one neuron is rapidly conveyed toExpand
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Properties and Plasticity of Paired-Pulse Depression at a Central Synapse
Synaptic depression was studied at the axo-axonic connection between the goldfish Mauthner axon and identified cranial relay interneurons using simultaneous presynaptic and postsynaptic recordingsExpand
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  • 9
Synergy between Electrical Coupling and Membrane Properties Promotes Strong Synchronization of Neurons of the Mesencephalic Trigeminal Nucleus
Electrical synapses are known to form networks of extensively coupled neurons in various regions of the mammalian brain. The mesencephalic trigeminal (MesV) nucleus, formed by the somata of primaryExpand
  • 79
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Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission.
While chemical synapses are very plastic and modifiable by defined activity patterns, gap junctions, which mediate electrical transmission, have been classically perceived as passive intercellularExpand
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Gap junction-mediated electrical transmission: regulatory mechanisms and plasticity.
The term synapse applies to cellular specializations that articulate the processing of information within neural circuits by providing a mechanism for the transfer of information between twoExpand
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Molecular and Functional Asymmetry at a Vertebrate Electrical Synapse
Electrical synapses are abundant in the vertebrate brain, but their functional and molecular complexities are still poorly understood. We report here that electrical synapses between auditoryExpand
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Connexin35 Mediates Electrical Transmission at Mixed Synapses on Mauthner Cells
Auditory afferents terminating as “large myelinated club endings” on goldfish Mauthner cells are identifiable “mixed” (electrical and chemical) synaptic terminals that offer the unique opportunity toExpand
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The extent and strength of electrical coupling between inferior olivary neurons is heterogeneous.
Gap junctions constitute the only form of synaptic communication between neurons in the inferior olive (IO), which gives rise to the climbing fibers innervating the cerebellar cortex. Although itsExpand
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Trafficking of gap junction channels at a vertebrate electrical synapse in vivo
Trafficking and turnover of transmitter receptors required to maintain and modify the strength of chemical synapses have been characterized extensively. In contrast, little is known regardingExpand
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Motoneuron properties during motor inhibition produced by microinjection of carbachol into the pontine reticular formation of the decerebrate cat.
It is well established that cholinergic agonists, when injected into the pontine reticular formation in cats, produce a generalized suppression of motor activity (1, 3, 6, 14, 18, 27, 33, 50). TheExpand
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