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Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).
Connexins (cx), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and suppression of the neoplastic phenotype. We used human brainExpand
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Tumor promotion by hydrogen peroxide in rat liver epithelial cells.
Reactive oxygen species, including H2O2, play an important role in the tumor promotion process. Using an in vitro model of tumor promotion involving the rat liver epithelial oval cell line T51B, theExpand
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Hydrogen peroxide promotes transformation of rat liver non‐neoplastic epithelial cells through activation of epidermal growth factor receptor
Previous studies demonstrated that hydrogen peroxide (H2O2) is a tumor promoter in the rat liver epithelial cell line T51B. We investigated the pathway linking H2O2 to tumor promotion. H2O2 canExpand
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Suppression of human fibrosarcoma cell growth by transcription factor, Egr‐1, involves down‐regulation of Bcl‐2
Previously, we showed that the transcription factor Egr‐1 suppressed the proliferation of v‐sis transformed NIH3T3 cells and also a number of human tumor cells. Here, we investigate the possibleExpand
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The Phytochemical Shikonin Stimulates Epithelial-Mesenchymal Transition (EMT) in Skin Wound Healing
Although various pharmacological activities of the shikonins have been documented, understanding the hierarchical regulation of these diverse bioactivities at the genome level is unsubstantiated. InExpand
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Participation of the ubiquitin-proteasome pathway in rat oocyte activation.
The role of the ubiquitin-proteasome pathway (UPP) in mitosis is well known. However, its role in meiotic division is still poorly documented, especially in the activation of mammalian oocytes. InExpand
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Effects of MAP kinase pathway and other factors on meiosis of Urechis unicinctus eggs
The eggs of Urechis unicinctus Von Drasche, an echiuroid, are arrested at P‐I stage in meiosis. The meiosis is reinitiated by fertilization. Immunoblotting analysis using anti‐ERK2 andExpand
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The effects of proteasome inhibitor lactacystin on mouse oocyte meiosis and first cleavage
In order to study the effects of ubiquitin-proteasome pathway (UPP) on mouse oocyte meiosis and cleavage, oocytes undergoing maturation and parthenogenetic activation and 1-cell embryos were treatedExpand
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Notice of RetractionROS and Ca²+ Signal Activator-Resveratrol Induce Human Hepatoma Cancer Cell HepG-2 Apoptosis
To study mechanism of resveratrol induce HepG-2 apoptosis via Ca2+ and ROS pathway. Measurements using mononuclear cell direct cytotoxicity assay(the MTT method) shows that its cytotoxic effect onExpand
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[Triptolide inhibites Th17 cell differentiation via regulating cyclooxygenase-2/ prostaglandin E2 axis in synovial fibroblasts from rheumatoid arthritis].
Triptolide (TPT), an active compound extracted from Chinese herb Tripterygium wilfordii , has been used in therapy of rheumatoid arthritis (RA). In this study, after synovial fibroblasts fromExpand
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