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Extended vs. short‐term buprenorphinenaloxone for treatment of opioid addicted youth: A randomized trial
Continuing treatment with buprenorphine-naloxone improved outcome compared with short-term detoxification, and extended medication-assisted therapy may be more helpful for young individuals with opioid dependence.
A genetic association study of the mu opioid receptor and severe opioid dependence
No evidence of association between the five mu opioid receptor polymorphisms studied and severe opioid dependence in the sample is found, however, significant allele frequency differences between African-Americans and European-Americans for all five polymorphisms, irrespective of drug-dependent status.
Non-prescribed use of pain relievers among adolescents in the United States.
The genetic determinants of smoking.
The scientific evidence that supports a role for genetic influences on smoking is reviewed, specific genetic and neurobiological mechanisms that may mediate susceptibility to nicotine dependence are discussed, possible gene/environmental interactions that may be important in understanding smoking behavior are identified, and directions for future research are suggested.
Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.
- Li-Tzy Wu, C. Ringwalt, P. Mannelli, A. Patkar
- Medicine, PsychologyJournal of the American Academy of Child and…
- 1 September 2008
Dependence on PPRs can occur without abuse, and subthreshold dependence deserves to be investigated further for consideration in major diagnostic classification systems.
Polypharmacy in schizophrenia
- P. Masand, H. Tharwani, A. Patkar
- Psychology, MedicineInternational journal of psychiatry in clinical…
- 1 January 2006
The evidence for the adjunctive use of antipsychotics, anticonvulsants, lithium, antidepressants, benzodiazepines and other psychotropics in the treatment of schizophrenia is reviewed, and suggestions toward use of polypharmacy in difficult and practical clinical settings are offered.
Buprenorphine implants for treatment of opioid dependence: a randomized controlled trial.
Among persons with opioid dependence, the use of buprenorphine implants compared with placebo resulted in less opioid use over 16 weeks as assessed by urine samples and a greater change on clinician global ratings of severity of opioid dependence.
Pre—Treatment Measures of Impulsivity, Aggression and Sensation Seeking Are Associated with Treatment Outcome for African—American Cocaine—Dependent Patients
- A. Patkar, Heather W. Murray, P. Mannelli, E. Gottheil, S. Weinstein, M. Vergare
- PsychologyJournal of addictive diseases
- 14 April 2004
Higher levels of pretreatment impulsivity and aggression and sensation seeking seem to associated with poor treatment outcome for cocaine dependent patients receiving intensive outpatient treatment, and a combination of the three variables contributed significantly toward predicting retention and abstinence.
Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: a pilot study on differential effects of sex hormones on antidepressant effects.
An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study.
- Li-Tzy Wu, Jeng-Jong Pan, J. Blaine
- Psychology, MedicineJournal of studies on alcohol and drugs
- 1 May 2009
Criterion symptoms of alcohol and marijuana dependences exhibited a high level of internal consistency, highlighting the clinical utility of the DSM-IV checklist in assessing alcohol- and marijuana dependence syndromes among treatment-seeking substance users.