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Terlipressin in patients with cirrhosis and type 1 hepatorenal syndrome: a retrospective multicenter study.
TLDR
In patients with type 1 HRS, terlipressin-induced improved renal function is associated with an increase in survival, and a randomized trial investigating the effect of ter Lipressin on survival in patients with types 1 and 2 HRS should be performed. Expand
Sulindac causes regression of rectal polyps in familial adenomatous polyposis.
TLDR
Sulindac is effective in inducing the regression of rectal polyps in familial adenomatous polyposis and an immunohistochemical study of the cellular proliferation index was not able to show a sulindac-induced modification of the Ki 67 index. Expand
Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1.
TLDR
These findings, and the cellular phenotype, suggest that codanin-1 may be involved in nuclear envelope integrity, conceivably related to microtubule attachments, as well as underlies normal erythropoiesis. Expand
Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery.
TLDR
Consumption of regular coffee but not espresso is an independent protective factor for liver fibrosis in severely obese European patients. Expand
Randomized controlled trial of tamoxifen in advanced hepatocellular carcinoma.
TLDR
In this large study, tamoxifen did not improve the survival of patients with advanced HCC, but there is a suggestion that patients without major hepatic insufficiency seem to have some survival benefit. Expand
A national survey of acute hepatitis E in France
TLDR
This study highlights the need to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds. Expand
CATSPER2, a human autosomal nonsyndromic male infertility gene
TLDR
To the best of the knowledge, the involvement of CATSPER2 in asthenoteratozoospermia is the first description of a human autosomal gene defect associated with nonsyndromic male infertility. Expand
Low Levels of 25-Hydroxy Vitamin D are Independently Associated with the Risk of Bacterial Infection in Cirrhotic Patients
TLDR
Low levels of 25-OH vitamin D were independently associated with bacterial infections in cirrhotic patients and should be assessed in randomized trials. Expand
Microscopic Colitis or Functional Bowel Disease With Diarrhea: A French Prospective Multicenter Study
TLDR
Age >50 years, the presence of nocturnal stools, weight loss, the introduction of a new drug, and the presenceof a known autoimmune disease increase the probability of MC and thus the indication for colonoscopy with biopsies. Expand
Epidemiological and prognostic factors involved in upper gastrointestinal bleeding: results of a French prospective multicenter study.
TLDR
UGIB still occurs mainly as a result of peptic ulcers and portal hypertension in France, and causes significant rates of mortality, and there is scope for improvement via better prevention, better use of UGIB-facilitating drugs, endoscopic therapy, and management of co-morbidities. Expand
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