• Publications
  • Influence
Antioxidant activity applying an improved ABTS radical cation decolorization assay.
A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and hydrophilic antioxidants, including flavonoids, hydroxycinnamates,Expand
The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition
Fruit and vegetables rich in anthocyanins demonstrated the highest antioxidant activities, followed by those rich in flavanones and flavonols, while the hydroxycinnamate-rich fruit consistently elicited the lower antioxidant activities. Expand
The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans.
While urinary, salivary, and plasma nitrate concentrations increased between 4- and 7-fold, a significant increase in nitrite was only detected in saliva (7-fold). Expand
Decomposition of cocoa procyanidins in the gastric milieu.
The effects of the acidic environment, as found in the gastric milieu, on procyanidin oligomers of catechin polyphenols has been investigated and it is shown that under these conditions the procyAnid in oligomers are hydrolysed to mixtures of epicatechin monomer and dimer, thus enhancing the potential for their absorption in the small intestine. Expand
Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation?
The data obtained suggest that hydroxycinnamates can act by one of two possible mechanisms: preferential nitration for monophenolates and electron donation by catecholates. Expand
The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth.
The ability of monomeric and dimeric flavanols to scavenge reactive nitrogen species derived from nitrous acid to highlight multiple routes in which dietary derived Flavanols may exert beneficial effects in the gastrointestinal tract. Expand
Interaction of peroxynitrite with carotenoids and tocopherols within low density lipoprotein
It was observed that the carotenoids were consumed by a significantly greater proportion than that of the tocopherols with lycopene being more reactive than β‐carotene when exposed to peroxynitrite (50 μM) for 1 min. Expand
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols.
The catechin polyphenols were found to offer protection from peroxynitrite-induced modification of critical amino acids of apolipoprotein B-100 of LDL which contribute towards its surface charge. Expand
Simultaneous Detection of the Antioxidant and Pro-oxidant Activity of Dietary Polyphenolics in a Peroxidase System
The ability to reduce the peroxidase (myeloglobin/H2O2)-generated ABTS•+ [2,2′-azinobis-(3-ethylbenzthiazoline-6-sulfonic acid) radical cation] has been used to rank the antioxidant activity ofExpand
Caffeic acid derivatives in artichoke extract are metabolised to phenolic acids in vivo
The caffeic acid esters found in the artichoke extract capsule are absorbed, metabolised and excreted as methylated phenolic acids such as ferulic, isoferulic, dihydroferulic and vanillic acid. Expand