• Publications
  • Influence
Horizontal gene transfer and bacterial diversity
  • C. Dutta, A. Pan
  • Biology, Medicine
  • Journal of Biosciences
  • 1 February 2002
Bacterial genomes are extremely dynamic and mosaic in nature. A substantial amount of genetic information is inserted into or deleted from such genomes through the process of horizontal transfer.Expand
Chaos game representation of proteins.
The present report proposes a new method for the chaos game representation (CGR) of different families of proteins. Using concatenated amino acid sequences of proteins belonging to a particularExpand
Identification and Characterization of Potential Therapeutic Candidates in Emerging Human Pathogen Mycobacterium abscessus: A Novel Hierarchical In Silico Approach
Mycobacterium abscessus, a non-tuberculous rapidly growing mycobacterium, is recognized as an emerging human pathogen causing a variety of infections ranging from skin and soft tissue infections toExpand
Unraveling novel broad-spectrum antibacterial targets in food and waterborne pathogens using comparative genomics and protein interaction network analysis.
Food and waterborne diseases are a growing concern in terms of human morbidity and mortality worldwide, even in the 21st century, emphasizing the need for new therapeutic interventions for theseExpand
Codon usage in highly expressed genes of Haemophillus influenzae and Mycobacterium tuberculosis: translational selection versus mutational bias.
Biases in the codon usage and base compositions at three codon sites in different genes of A+T-rich Gram-negative bacterium Haemophillus influenzae and G+C-rich Gram-positive bacterium MycobacteriumExpand
Computational Approaches and Related Tools to Identify MicroRNAs in a Species: A Bird’s Eye View
MicroRNAs (miRNAs) are a family of non-coding RNAs that play a central role in fine-tuning gene expression regulation. Over the past decade, identification and annotation of miRNAs have become aExpand
Identification of potential drug targets in Yersinia pestis using metabolic pathway analysis: MurE ligase as a case study.
  • A. Sharma, A. Pan
  • Biology, Medicine
  • European journal of medicinal chemistry
  • 1 November 2012
Sporadic outbreaks of plague, lack of a vaccine, emergence of multidrug-resistant strains of Yersinia pestis, and its potential use in bioterrorism, call for an urgent need to develop new drugs forExpand
Computational analysis of protein interaction networks for infectious diseases
We discuss various computational approaches for analysing protein interaction networks in context to infectious diseases. Expand
A Bioinformatics Resource for TWEAK-Fn14 Signaling Pathway
TNF-related weak inducer of apoptosis (TWEAK) is a new member of the TNF superfamily. It signals through TNFRSF12A, commonly known as Fn14. The TWEAK-Fn14 interaction regulates cellular activitiesExpand
Compositional variation in bacterial genes and proteins with potential expression level
Usage of guanine and cytosine at three codon sites in eubacterial genes vary distinctly with potential expressivity, as predicted by Codon Adaptation Index (CAI). In bacteria with moderate/highExpand