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Effective mutations in a high redox potential laccase from Pleurotus ostreatus
Since the first report on a laccase, there has been a notable development in the interest towards this class of enzymes, highlighted from the number of scientific papers and patents about them. AtExpand
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Technical advances in proteomics mass spectrometry: identification of post-translational modifications
Abstract The importance of post-translational modifications (PTMs) of proteins has become evident in the proteomic era as it plays a critical role in modulating cellular function, and can vary inExpand
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A family GH51 α-l-arabinofuranosidase from Pleurotus ostreatus: identification, recombinant expression and characterization
An α-l-arabinofuranosidase produced by Pleurotus ostreatus (PoAbf) during solid state fermentation on tomato pomace was identified and the corresponding gene and cDNA were cloned and sequenced.Expand
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Demonstration of physicochemical and functional similarity between the proposed biosimilar adalimumab MSB11022 and Humira®
ABSTRACT Biosimilars are biological products that are highly similar to existing products approved by health authorities. Demonstration of similarity starts with the comprehensive analysis of theExpand
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Quantitative identification of protein nitration sites
Several labelling strategies have been developed targeting specific amino acid residues and/or PTMs. Methods specifically tailored for the qualitative and sometimes quantitative determination of PTMsExpand
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Plasma nitroproteome of kidney disease patients
Abstract3′-nitrotyrosine (3NT) is a post-translational modification (PTM) of body fluids and tissues that is sustained by chronic inflammation and oxidative stress, two main clinical traits ofExpand
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Privileged Incorporation of Selenium as Selenocysteine in Lactobacillus reuteri Proteins Demonstrated by Selenium-specific Imaging and Proteomics*
An analytical approach was developed to study the incorporation of selenium (Se), an important trace element involved in the protection of cells from oxidative stress, into the well-known probioticExpand
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Novel method to investigate protein carbonylation by iTRAQ strategy
AbstractThis paper reports a novel methodology for relative quantitative analysis of carbonylation sites in proteins by exploiting a new isobaric tag for relative and absolute quantitation (iTRAQ)Expand
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Site-specific N- and O-glycosylation analysis of atacicept
ABSTRACT The Fc-fusion protein atacicept is currently under clinical investigation for its biotherapeutic application in autoimmune diseases owing to its ability to bind the two cytokinesExpand
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Privileged incorporation of selenium as selenocysteine in Lactobacillus reuteri proteins demonstrated by selenium-specific imaging and proteomics
An analytical approach was developed to study the incorporation of selenium (Se), an important trace element involved in the protection of cells from oxidative stress, into the well-known probioticExpand
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