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Non‐clinical toxicity of &bgr;‐caryophyllene, a dietary cannabinoid: Absence of adverse effects in female Swiss mice
- G. L. da Silva Oliveira, K. C. Machado, K. C. Machado, A. P. D. S. C. D. da Silva, C. Feitosa, Fernanda Regina de Castro Almeida
- Regulatory toxicology and pharmacology : RTP
- 1 February 2018
The results of this study provide an understanding of the toxicity profile of &bgr;‐caryophyllene which can be considered a compound with toxicity at doses higher than 2000 mg/kg body weight. Expand
Pre-clinical toxicology of garcinielliptone FC, a tautomeric pair of polyprenylated benzophenone, isolated from Platonia insignis Mart seeds.
- A. P. D. S. C. D. da Silva, G. L. S. Oliveira, +5 authors R. M. de Freitas
- Phytomedicine : international journal of…
- 15 May 2016
The acute toxicity study indicated that GFC treatment, at selected doses given orally and intraperitoneally, showed relatively low risk of toxicity in all test animals, suggesting that it is safe for further investigation. Expand
Evaluation of the non-clinical toxicity of an antiparasitic agent: diminazene aceturate.
DIZE induces several adverse effects with influence on the central nervous system, changes in hematological and biochemical parameters and even mortality at the highest dose, however, absence of toxicity was observed in A. salina and rats red blood cells. Expand