• Publications
  • Influence
CNS Region-Specific Oxytocin Receptor Expression: Importance in Regulation of Anxiety and Sex Behavior
The oxytocin receptor (OTR) is differentially expressed in the CNS. Because there are multiple mechanisms by which the OTR can be transcriptionally induced, we hypothesized that differences in OTRExpand
  • 373
  • 18
  • PDF
The Epigenetics of Sex Differences in the Brain
Epigenetic changes in the nervous system are emerging as a critical component of enduring effects induced by early life experience, hormonal exposure, trauma and injury, or learning and memory. SexExpand
  • 350
  • 11
  • PDF
Sex differences in epigenetic regulation of the estrogen receptor-alpha promoter within the developing preoptic area.
Sex differences in the brain are largely organized by a testicular hormone surge that occurs in males shortly after birth. Although this hormone surge is transient, sex differences in brain andExpand
  • 160
  • 7
Getting excited about GABA and sex differences in the brain
In a unique reversal of function, the ubiquitous and dominant inhibitory neurotransmitter, GABA, serves as the major source of neuronal excitation in the developing brain. Opening of voltage-gatedExpand
  • 125
  • 7
  • PDF
Winning territorial disputes selectively enhances androgen sensitivity in neural pathways related to motivation and social aggression
Winning aggressive disputes can enhance future fighting ability and the desire to seek out additional contests. In some instances, these effects are long lasting and vary in response to the physicalExpand
  • 163
  • 7
  • PDF
Brain Sex Differences and the Organisation of Juvenile Social Play Behaviour
Juvenile social play behaviour is one of the earliest forms of non‐mother directed social behaviour in rodents. Juvenile social play behaviour is sexually dimorphic, with males exhibiting higherExpand
  • 91
  • 6
Epigenetic control of vasopressin expression is maintained by steroid hormones in the adult male rat brain
Although some DNA methylation patterns are altered by steroid hormone exposure in the developing brain, less is known about how changes in steroid hormone levels influence DNA methylation patterns inExpand
  • 83
  • 4
  • PDF
Excitatory versus inhibitory GABA as a divergence point in steroid-mediated sexual differentiation of the brain
Whereas adult sex differences in brain morphology and behavior result from developmental exposure to steroid hormones, the mechanism by which steroids differentiate the brain is unknown. Studies toExpand
  • 62
  • 4
  • PDF
Sex difference in the phosphorylation of cAMP response element binding protein (CREB) in neonatal rat brain
On the day of birth, a surge in testicular testosterone release in male rats is critical for sexual differentiation of the brain. Steroid hormones function by binding to intracellular steroidExpand
  • 52
  • 4
Sex Difference in the Expression of DNA Methyltransferase 3a in the Rat Amygdala During Development
Sexual differentiation of the neonatal rat brain is regulated by dynamic processes occurring at the level of DNA, resulting in sexually dimorphic gene expression. Steroid hormone receptors act partlyExpand
  • 68
  • 4