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[Genetic processes and the problem of the target in chromosomal mutagenesis].
Based on analysis of literature data and the data of the authors, it is assumed that there are two main mechanisms of formation of structural chromosome mutations in eukaryotic cells: 1) homologous… Expand
[Reproduction in the second nuclear cycle of chromosome aberrations induced in the G2 phase of Crepis capillaris cells by gamma rays, 5-fluoro-2-deoxyuridine and their combined action].
[The concept of base genome and critical mass of eukaryotic chromosomes].
- A. P. Akif'ev
- Doklady Akademii nauk
[Chromosome aberrations, chromatin diminution and their significance in understanding the molecular genetic organization of eukaryotic chromosomes].
- A. P. Akif'ev, I. I. Beliaev, A. Grishanin, S. V. Degtiarev, G. A. Khudolii
- Radiatsionnaia biologiia, radioecologiia
The paper analyzes the significance of new data obtained in the study of mechanism of formation of radiation-induced chromosome aberrations and in the investigation of chromatin diminution for… Expand
[The biological aspects of chromatin diminution].
The chromatine diminution (CD), first discovered by Boveri (1887) in ascarids, represents programmed elimination of a part of genetic material in the nuclei of the somatic cells in cyclops and… Expand
[Mutagenesis and genetic homeostasis in higher organisms].
Structural genes and genetic regulatory sites occupy merely a small space in the eukaryotic genome; the remaining space presents various uncoding sequences. Genomic reorganizations, i.e. changes in… Expand
[Nuclear genetic material as an initial substrate for animal aging].
General properties of aging in animals are considered on the basis of the literature evidence and the results obtained by the authors of this paper. The existence of a specific aging mechanism is… Expand
[Molecular mechanisms of formation of chromosome aberrations].
[Radiation-induced shortening of the lifespan of D. melanogaster. 2. Sensitizing effect of 5-bromo-2-deoxyuridine].
[Noninduced local DNA synthesis in the G1 phase and its relationship to chromosomal mutagenesis].