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Amelioration of carbon tetrachloride-induced hepatotoxicity and haemotoxicity by aqueous leaf extract of Cnidoscolus aconitifolius in rats.
This study was conducted to explore possible protective effect ofCnidoscolus aconitifolius (CA) leaf extract on carbon tetrachloride (CCl4)-induced hepatotoxicity and haemotoxicity in experimentalExpand
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Failure of recovery from lead induced hepatoxicity and disruption of erythrocyte antioxidant defence system in Wistar rats.
Lead acetate (PbA) is one of the major environmental contaminants with grave toxicological consequences both in the developing and developed countries. The liver and erythrocyte antioxidant statusExpand
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Assessment of chronic administration of Aloe vera gel on haematology, plasma biochemistry, lipid profiles and erythrocyte osmotic resistance in Wistar rats.
The study was designed to investigate the effects of chronic administration of Aloe vera gel extract on markers of hepatic damage, lipid profiles and erythrocyte osmotic fragility using the WistarExpand
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Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract.
OBJECTIVE To explore the antidiabetic properties of Mucuna pruriens(M. pruriens). METHODS Diabetes was induced in Wistar rats by single intravenous injection of 120 mg/kg of alloxan monohydrate andExpand
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Ameliorative effects of Cnidoscolus aconitifolius on alloxan toxicity in Wistar rats.
BACKGROUND Diabetes has been associated with several complications occasioned by oxidative stress. Thus, in treatment of the condition, these complications must also be taken into consideration. ThisExpand
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Toxicological evaluations of methanolic extract of Moringa oleifera leaves in liver and kidney of male Wistar rats
Abstract Background: This study was conducted to investigate toxicological effects associated with prolonged consumption of Moringa oleifera leaves as a beverage. Methods: Thirty rats were used inExpand
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Evaluation of antimalarial and antioxidant activities of the methanol seed extract of Adenanthera pavonina (Linn) in Plasmodium berghei infected mice
Objectives: Malaria and oxidative stress are major health problems in the world in general. The goal of the study is to investigate the antimalarial and antioxidant activities of the methanol seedExpand
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Molecular targets of [6]‐gingerol: Its potential roles in cancer chemoprevention
A wide variety of phenolic compounds derived from spices possess potent antioxidant, anti‐inflammatory, antimutagenic, and anticarcinogenic activities. [6]‐gingerolExpand
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Lack of reversal of oxidative damage in renal tissues of lead acetate-treated rats.
Removal of lead from the environment of man or otherwise, the movement of man from lead-contaminated areas has been employed as a means of abatement of the toxic effects of lead. Whether toxicExpand
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Interactions between reactive oxygen species and cancer: the roles of natural dietary antioxidants and their molecular mechanisms of action.
Reactive oxygen species (ROS) are natural products inevitably generated along with cellular metabolism. Due to their extreme reactivity, they can damage DNA, proteins and lipids. Dietary antioxidantsExpand
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