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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.
A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virusExpand
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A newly discovered human pneumovirus isolated from young children with respiratory tract disease
From 28 young children in the Netherlands, we isolated a paramyxovirus that was identified as a tentative new member of the Metapneumovirus genus based on virological data, sequence homology and geneExpand
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
BACKGROUND The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent. METHODS ClinicalExpand
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Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, andExpand
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Mapping the Antigenic and Genetic Evolution of Influenza Virus
The antigenic evolution of influenza A (H3N2) virus was quantified and visualized from its introduction into humans in 1968 to 2003. Although there was remarkable correspondence between antigenic andExpand
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Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
Most human coronaviruses cause mild upper respiratory tract disease but may be associated with more severe pulmonary disease in immunocompromised individuals. However, SARS coronavirus caused severeExpand
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Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets
Avian flu can acquire the capacity for airborne transmission between mammals without recombination in an intermediate host. Highly pathogenic avian influenza A/H5N1 virus can cause morbidity andExpand
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Spatial, Temporal, and Species Variation in Prevalence of Influenza A Viruses in Wild Migratory Birds
Although extensive data exist on avian influenza in wild birds in North America, limited information is available from elsewhere, including Europe. Here, molecular diagnostic tools were employed forExpand
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Clearance of influenza virus from the lung depends on migratory langerin+CD11b− but not plasmacytoid dendritic cells
Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b− and CD11b+ conventional DCs or plasmacytoidExpand
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Analysis of the genomic sequence of a human metapneumovirus.
We recently described the isolation of a novel paramyxovirus from children with respiratory tract disease in The Netherlands. Based on biological properties and limited sequence information the virusExpand
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