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Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic disorders. Therefore, a reduction in VAT has become a key goal in obesity management. However, VAT isExpand
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The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis
Brown fat activates uncoupled respiration in response to cold temperature and contributes to systemic metabolic homeostasis. To date, the metabolic action of brown fat has been primarily attributedExpand
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Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity.
Although 5%-10% weight loss is routinely recommended for people with obesity, the precise effects of 5% and further weight loss on metabolic health are unclear. We conducted a randomized controlledExpand
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Ageratum conyzoides L. (Asteraceae).
  • A. Okunade
  • Biology, Medicine
  • Fitoterapia
  • 1 February 2002
Ageratum conyzoides L., is an annual herb with a long history of traditional medicinal uses in many countries in the world, especially in the tropical and subtropical regions. A wide range ofExpand
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Role of Fat Body Lipogenesis in Protection against the Effects of Caloric Overload in Drosophila*
Background: A high sugar diet leads to obesity and insulin resistance in Drosophila. Results: The metabolic fate of dietary glucose is reprogrammed in high sugar-fed and lean animals. Conclusion:Expand
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WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation.
WNT signaling controls many biological processes including cell differentiation in metazoans. However, how WNT reprograms cell identity is not well understood. We have investigated the potential roleExpand
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Metabolically normal obese people are protected from adverse effects following weight gain.
BACKGROUND. Obesity is associated with insulin resistance and increased intrahepatic triglyceride (IHTG) content, both of which are key risk factors for diabetes and cardiovascular disease. However,Expand
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Natural antimycobacterial metabolites: current status.
Over the years the introduction of very effective drugs has revolutionized the treatment of tuberculosis. In recent years, however, emerging multiple drug resistance has become a major threat andExpand
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Antiplasmodial activity of extracts and quassinoids isolated from seedlings of Ailanthus altissima (Simaroubaceae).
Extracts and isolated compounds from seedlings of Ailanthus altissima, were assessed for antiplasmodial activity in vitro. Two quassinoids, ailanthone and 6alpha-tigloyloxychaparrinone, isolated fromExpand
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CD36 level and trafficking are determinants of lipolysis in adipocytes
CD36 has been linked to the etiology of insulin resistance and inflammation. We explored its function in regulating adipose tissue lipolysis, which influences fat accumulation by liver and muscle andExpand
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