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Bone marrow transplantation for T−B− severe combined immunodeficiency disease in Athabascan-speaking native Americans
The results demonstrate the efficacy of BMT in treating infants with this distinct form of SCID, although B cell reconstitution remains a problem even with HLA-matched donors.
Oral and genital ulceration: a unique presentation of immunodeficiency in Athabascan-speaking American Indian children with severe combined immunodeficiency.
Oral and/or genital ulceration appears to be an important, distinctive finding, and often a presenting feature of immunodeficiency in Athabascan-speaking American Indian children with SCID.
Successful resection of thoracic aortic aneurysms in Wiskott-Aldrich syndrome.
A 23-year-old man with Wiskott-Aldrich syndrome, chronic aortitis, and severe aneurysmal dilatation of the thoracic aorta successfully underwent two-stage graft replacement of the ascending and
Bone marrow transplantation for inherited diseases.
Some of the unique features of bone marrow transplantation for inherited diseases are described and significant problems remain such as donor availability, conditioning regimen toxicity, graft failure, and graft-versus-host disease.
Cessation of unsuccessful pediatric resuscitation--how long is too long?
It is concluded that no consensus exists among the groups studied on the optimal duration of unsuccessful resuscitative efforts in pediatric patients, and it is speculated that the opinions might be more uniform if resuscitation of pediatric patients was provided primarily by pediatricians or PALS-certified physicians.