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Guideline for management of the clinical T1 renal mass.
Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors.
PURPOSE Laparoscopic partial nephrectomy is an increasingly performed, minimally invasive alternative to open partial nephrectomy. We compared early postoperative outcomes in 1,800 patients… Expand
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
- Jonathan M. Shillingford, N. Murcia, +11 authors T. Weimbs
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 4 April 2006
Autosomal-dominant polycystic kidney disease (ADPKD) is a common genetic disorder that frequently leads to renal failure. Mutations in polycystin-1 (PC1) underlie most cases of ADPKD, but the… Expand
Nephron sparing surgery for renal tumors: indications, techniques and outcomes.
PURPOSE A contemporary review of the indications, techniques and outcomes is presented for nephron sparing approaches to solid renal masses, emphasizing their role for the treatment of renal cell… Expand
Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients.
PURPOSE Laparoscopic partial nephrectomy is an emerging minimally invasive, nephron sparing approach for renal cell carcinoma. We compared perioperative outcomes after laparoscopic and open nephron… Expand
Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup.
PURPOSE Partial nephrectomy is effective for renal cell carcinoma when preservation of renal function is a concern. We present the 10-year followup of patients treated with nephron sparing surgery at… Expand
Factors predicting renal functional outcome after partial nephrectomy.
PURPOSE Compared to radical nephrectomy, partial nephrectomy better preserves renal parenchyma and function. Although several clinical factors may impact renal function after partial nephrectomy… Expand
Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid.
PURPOSE Angiomyolipomas classically present radiographically as fat containing lesions but some fail to demonstrate fat content. Histologically confirmed angiomyolipomas uniformly follow a benign… Expand
Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus cyclosporine1
Background. Progressive nephrotoxicity caused by calcineurin inhibitor drugs contributes to the long-term decline in renal function in kidney transplant patients. Methods. We conducted a randomized,… Expand
Renal mass biopsy--a renaissance?
PURPOSE Advances in our understanding of the natural history and limited aggressive potential of many small renal masses, expanding treatment options and the integration of molecular factors into… Expand