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Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis
Summary Background Schizophrenia is one of the most common, burdensome, and costly psychiatric disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is controversyExpand
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Efficacy, Acceptability, and Tolerability of Antipsychotics in Treatment-Resistant Schizophrenia: A Network Meta-analysis.
IMPORTANCE In treatment-resistant schizophrenia, clozapine is considered the standard treatment. However, clozapine use has restrictions owing to its many adverse effects. Moreover, an increasingExpand
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Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials
Abstract Objective To evaluate differences in downstream testing, coronary revascularisation, and clinical outcomes following non-invasive diagnostic modalities used to detect coronary arteryExpand
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Characteristics of Networks of Interventions: A Description of a Database of 186 Published Networks
Systematic reviews that employ network meta-analysis are undertaken and published with increasing frequency while related statistical methodology is evolving. Future statistical developments andExpand
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Demystifying fixed and random effects meta-analysis
Objective Systematic reviewers often need to choose between two statistical methods when synthesising evidence in a meta-analysis: the fixed effect and the random effects models. The two approachesExpand
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Systematic review of interventions for treating or preventing antipsychotic-induced tardive dyskinesia.
BACKGROUND Antipsychotic medication can cause tardive dyskinesia (TD) - late-onset, involuntary, repetitive movements, often involving the face and tongue. TD occurs in > 20% of adults takingExpand
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Planning future studies based on the precision of network meta-analysis results.
When there are multiple competing interventions for a healthcare problem, the design of new studies could be based on the entire network of evidence as reflected in a network meta-analysis. There isExpand
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Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis
  • M. Krause, Y. Zhu, +4 authors S. Leucht
  • Medicine, Psychology
  • European Archives of Psychiatry and Clinical…
  • 24 January 2018
BackgroundNegative symptoms are the core of schizophrenia, but whether antipsychotics are efficacious for their treatment is unclear. Moreover, there is debate whether patients in relevant trialsExpand
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Characteristics and knowledge synthesis approach for 456 network meta-analyses: a scoping review
BackgroundNetwork meta-analysis (NMA) has become a popular method to compare more than two treatments. This scoping review aimed to explore the characteristics and methodological quality of knowledgeExpand
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Endoscopic and Open Release Similarly Safe for the Treatment of Carpal Tunnel Syndrome. A Systematic Review and Meta-Analysis
BACKGROUND The Endoscopic Release of Carpal Tunnel Syndrome (ECTR) is a minimal invasive approach for the treatment of Carpal Tunnel Syndrome. There is scepticism regarding the safety of thisExpand
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