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Gametocyte sex ratios as indirect measures of outcrossing rates in malaria.
The frequency of recombination between unlike genotypes is central to understanding the generation of genetic diversity in natural populations of malaria. Here we suggest a way of investigating theExpand
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The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials. I. Malariometric indices and immunity.
The epidemiological features of malaria were studied through seven community-based surveys in a population of 4000 in the Wosera area, East Sepik Province, Papua New Guinea. Prevalence ofExpand
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Dynamics of malaria parasitaemia associated with febrile illness in children from a rural area of Madang, Papua New Guinea.
Active community and self-reporting surveillance techniques have been used to describe the dynamics of febrile illness and associated malaria infection in children aged 2 to 15 years from a ruralExpand
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Relationships between Plasmodium falciparum infection and morbidity in a highly endemic area.
A total of 736 outpatients diagnosed as having malaria using clinical criteria at a health centre in a highly endemic area of Papua New Guinea were investigated parasitologically. PlasmodiumExpand
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Age- and species-specific duration of infection in asymptomatic malaria infections in Papua New Guinea.
The burden and duration of asymptomatic malaria infections were measured in residents of the malaria endemic village of Gonoa, Madang Province, Papua New Guinea. Plasmodium falciparum, P. vivax andExpand
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Malaria: how useful are clinical criteria for improving the diagnosis in a highly endemic area?
To assess the validity of clinical criteria, we investigated 2096 outpatients diagnosed as malaria cases by nurses at a rural health subcentre in a highly endemic area of Papua New Guinea. 73% of theExpand
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Prospective risk of morbidity in relation to malaria infection in an area of high endemicity of multiple species of Plasmodium.
In an area of Papua New Guinea with high prevalence of Plasmodium falciparum (39.6%), Plasmodium vivax (18.3%), and Plasmodium malariae (13.8%), cross-sectional analysis found P. falciparum infectionExpand
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Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
The in vivo response of Plasmodium falciparum parasites to amodiaquine or chloroquine was assessed in children with symptomatic malaria attending different health facilities in the Madang area. AmongExpand
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Resistance of Plasmodium falciparum to amodiaquine in Papua New Guinea.
The sensitivity of Plasmodium falciparum to amodiaquine was assessed in children in the Madang region of Papua New Guinea. Fifty-four tests in vivo were carried out and 19 (35%) of these showedExpand
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The use of the polymerase chain reaction for more sensitive detection of Plasmodium falciparum.
The prevalence of Plasmodium falciparum in children and adults living in a malaria-endemic area in Papua New Guinea was determined by microscopy and by polymerase chain reaction (PCR). TheExpand
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