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Widespread transmission of independent cancer lineages within multiple bivalve species
Most cancers arise from oncogenic changes in the genomes of somatic cells, and while the cells may migrate by metastasis, they remain within that single individual. Natural transmission of cancerExpand
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Identification and phylogenetic comparison of p53 in two distinct mussel species (Mytilus).
The extent to which humans and wildlife are exposed to anthropogenic challenges is an important focus of environmental research. Potential use of p53 gene family marker(s) for aquatic environmentalExpand
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Population dynamics and metabolic activity of Pseudomonas abietaniphila BKME-9 within pulp mill wastewater microbial communities assayed by competitive PCR and RT-PCR
Resin acids contribute to the acute toxicity of pulp and paper mill effluent. We monitored the abundance and metabolic activity of the resin acid degrader, Pseudomonas abietaniphila BKME-9, withinExpand
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Activation of transcription and retrotransposition of a novel retroelement, Steamer, in neoplastic hemocytes of the mollusk Mya arenaria
Significance The soft shell clam in many areas of the North Atlantic is afflicted with a fatal leukemia-like disease of unknown origin. Leukemic cells from the diseased animals were found to releaseExpand
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Identification of DeltaN Isoform and Polyadenylation Site Choice Variants in Molluscan p63/p73-Like Homologues
The p53 family of transcription factors has been implicated in many vertebrate cancers. Altered p53 and p73 protein expression observed in leukemic cells of molluscs suggests that these transcriptionExpand
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Invertebrate p53-like mRNA isoforms are differentially expressed in mussel haemic neoplasia.
Mussels of the genus Mytilus are widely used in environmental monitoring. They can develop a leukaemia-like disease, haemic neoplasia, which could be induced, in part, by environmental stressors. TheExpand
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RNA/DNA ratio as an indicator of metabolic activity in resin acid-degrading bacteria
We investigated the relationship between the growth rate and the ratio of RNA to DNA in of four resin acid degrading bacteria isolated from a sequencing batch reactor (SBR). Chemical assays as wellExpand
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Variations in p53-like cDNA sequence are correlated with mussel haemic neoplasia: A potential molecular-level tool for biomonitoring.
Several bivalve species, including mussels (Mytilus spp.) and clams (Mya spp.), are susceptible to a leukemia-like disease called haemic neoplasia that has been known to decimate whole populations.Expand
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A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe
Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasiaExpand
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Low Variation in a Y-Chromosomal Growth Hormone Pseudogene Relative to its Functional Autosomal Progenitor Gene in Chinook Salmon
AbstractMost fish species do not have single-chromosome-based sex determination or display cytologically distinguishable sex chromosomes. The selective forces acting on homologous sequences inExpand
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