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Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents.
- A. Mosnaim, V. Ranade, M. Wolf, J. Puente, M. Antonieta Valenzuela
- Chemistry, BiologyAmerican Journal of Therapeutics
- 1 May 2006
The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes and could lead to the design of new therapeutic treatment modalities for conditions such as Alzeimer's and Creutzfeldt-Jakob disease.
Pathways linkingl-phenylalanine and 2-phenylethylamine withp-tyramine in rabbit brain
A review of orthostatic blood pressure regulation and its association with mood and cognition
This paper will review literature that examines the psychological and neuropsychological correlates of orthostatic blood pressure regulation and identify possible causes and consequences of subclinical and clinical OH.
Matrix metalloproteinase profile in patients with Creuztfeldt-Jakob disease.
Preliminary findings suggest that abnormalities in matrix metalloproteinase (MMP) activity may be found in the cerebrospinal fluid (CSF) of patients with Creutzfeldt-Jakob disease (CJD). In this…
A review of the etiology, associated comorbidities, and treatment of orthostatic hypotension.
- L. Perlmuter, Garima Sarda, Vanessa Casavant, A. Mosnaim
- Psychology, MedicineAmerican Journal of Therapeutics
- 1 May 2013
A better understanding of the underlying causes responsible for the etiology of OH could lead to a rational design of novel effective therapeutic regimens for the treatment of this condition and associated comorbidities.
Brain 2-phenylethylamine as a major mediator for the central actions of amphetamine and methylphenidate.
Posttraumatic Stress Disorder: Etiology, Phenomenology, and Treatment
This work has focused on the relationship between biological mechanisms and pharmacotherapy of posttraumatic stress disorder, and the role of antidepressants and psychotherapeutic interventions in the treatment of this disorder.
Etiology and Risk Factors for Developing Orthostatic Hypotension
- A. Mosnaim, Rasheed Abiola, M. Wolf, L. Perlmuter
- Medicine, PsychologyAmerican journal of therapeutics
- 1 January 2010
Factors should be considered when diagnosing OH and when prescribing remedies for both patients with OH and those without OH; medication's contributions to the severity and/or risk of developing OH could limit their use.
Studies in the mechanism of phenylethylamine uptake by rabbit erythrocytes.