• Publications
  • Influence
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
TLDR
In patients with acute lung injury and the acute respiratory distress syndrome, mechanical ventilation with a lower tidal volume than is traditionally used results in decreased mortality and increases the number of days without ventilator use.
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome.
TLDR
In patients with acute lung injury and ARDS who receive mechanical ventilation with a tidal-volume goal of 6 ml per kilogram of predicted body weight and an end-inspiratory plateau-pressure limit of 30 cm of water, clinical outcomes are similar whether lower or higher PEEP levels are used.
Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.
TLDR
It is concluded that ECMO can support respiratory gas exchange but did not increase the probability of long-term survival in patients with severe ARF.
Lung volumes in healthy nonsmoking adults.
TLDR
Total lung capacity, functional residual capacity, residual volume, and corresponding 95% confidence intervals were measured in 245 healthy nonsmoking person using a single-breath helium technique and radial TLC was not significantly different from the helium dilution TLC.
Reference spirometric values using techniques and equipment that meet ATS recommendations.
TLDR
This study produced predicted values for forced vital capacity and forced expiratory volume in one second that were almost identical to those predicted by Morris and associates when the data from their study were modified to be compatible with the back extrapolation technique recommended by the ATS.
Randomized clinical trial of pressure-controlled inverse ratio ventilation and extracorporeal CO2 removal for adult respiratory distress syndrome.
TLDR
It is concluded that there was no significant difference in survival between the mechanical ventilation and the extracorporeal CO2 removal groups, and extracordoreal support for ARDS should be restricted to controlled clinical trials.
Standardized single breath normal values for carbon monoxide diffusing capacity.
TLDR
Prediction equations for DLCO and diffusing capacity per unit of lung volume (DL/VA) were generated from 245 normal subjects using a standardized technique for measuring DLCO using standard and robust regression techniques, predicting values that were higher than most previously reported values.
Incidence of the adult respiratory distress syndrome in the state of Utah.
  • G. Thomsen, A. Morris
  • Medicine
    American journal of respiratory and critical care…
  • 1 September 1995
TLDR
The incidence of ARDS in Utah is about an order of magnitude less than the 1972 National Heart and Lung Institute Task Force estimate of AR DS incidence in the United States, but agrees with more recently published ARDS incidence figures.
Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.
TLDR
In patients with acute lung injury, a strategy of initial trophic enteral feeding for up to 6 days did not improve ventilator-free days, 60-day mortality, or infectious complications but was associated with less gastrointestinal intolerance.
Hyperbaric oxygen for acute carbon monoxide poisoning.
TLDR
Three hyperbaric-oxygen treatments within a 24-hour period appeared to reduce the risk of cognitive sequelae 6 weeks and 12 months after acute carbon monoxide poisoning.
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