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Triterpenes from Stauntonia hexaphylla callus tissues
A new triterpene 1 has been isolated from the extract of Stautonia hexaphylla callus tissues. The structure was elucidated as 3α-hydroxy-11α, 12α-epoxyoleanan- 28, 13β-olide [1] by 1 H-nmr, 13 C-nmr,Expand
A facile method for the oxidation of alcohols.
Trialkyltin alkoxides, prepared from alcohols and trialkyltin methoxide by azeotropical removal of methanol, are easily oxidized by bromine in the presence of trialkyltin methoxide, a hydrogenExpand
5-Isoquinolinesulfonamide derivatives. 2. Synthesis and vasodilatory activity of N-(2-aminoethyl)-5-isoquinolinesulfonamide derivatives.
A new series of aromatic sulfonamides, the N-(2-aminoethyl)-5-isoquinolinesulfonamide derivatives, 3, was synthesized from 5-isoquinolinesulfonic acid and shown to possess vasodilatory action.Expand
Efficient Methods for Oxidation of Alcohols
Treatment of alkoxymagnesium bromides, prepared in situ from alcohols and Grignard reagent, with N-chlorosuccinimide, m-chloroperbenzoic acid, or (diacetoxyiodo)benzene in the presence ofExpand
A saponin from callus tissue of Stauntonia hexaphylla.
A new 30-nortriterpenoid saponin was isolated from the callus tissues of Stauntonia hexaphylla. The structure of the saponin (tentatively named mubenoside A) was elucidated as 3 beta,20Expand
5-Isoquinolinesulfonamide derivatives. III. Synthesis and vasodilatory activity of 1-(5-isoquinoline-sulfonyl)piperazine derivatives.
On the basis of a hypothesis that cyclization and alkylation of the diamine part in formula 1 may give highly active compounds, a new series of 5-isoquinolinesulfonamide derivatives, shown as formulaExpand
Novel Partial Protections of 1, 6–Anhtdro–β-Lactose
ABSTRACT 1, 6-Anhydro-β-lactose (3) was prepared as its peracetate (2) from lactose monohydrate via its pentachlorophenyl β-lactoside derivative in 49% overall yield. Treatment of the 4′, 6′Expand
5-Isoquinolinesulfonamide derivatives. 1. Synthesis and vasodilatory activity of N-(2-guanidinoethyl)-5-isoquinolinesulfonamide derivatives.
Two novel series of N-(2-guanidinoalkyl)-5-isoquinolinesulfonamides, 2 and 3, were prepared. Many of the compounds possessed vasodilatory activity when injected locally into the femoral artery ofExpand