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Characterization of glutathione S-transferase activity in Echinococcus granulosus.
1. Glutathione S-transferase activity has been characterized in protoscolices of Echinococcus granulosus. 2. The conjugation reaction was activated by treatment of protoscolices with phenobarbitalExpand
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Metabolism of juvenile hormone with isolated rat hepatocytes.
Abstract The metabolism of juvenile hormone I has been examined in rat hepatocyte suspensions. The hormone penetrates rapidly into the cells where its concentration becomes higher than in theExpand
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Some spectral properties of cytochrome P-450 from microsomes isolated from control, phenobarbital- and naphthalene-treated houseflies.
Abstract 1. Phenobarbital and naphthalene induce a new species of cytochrome P-450 in houseflies which has a maximum absorbance in the off balance absolute spectrum at 446 nm. 2. Neither induced norExpand
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Fate of juvenile hormone in mammalian cell culture.
The metabolism of juvenile hormone (JH) I has been examined in fetal mouse liver cells maintained in culture. Diffusion of the hormone into the cells appears to be passive. The hormone is metabolizedExpand
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Cytochrome P-450 and hydroxylating activity of microsomal preparations from whole houseflies.
1. A new microsomal preparation, obtained from whole houseflies is described in terms of its cytochrome P-450 content and its hydroxylating activity. 2. Microsomes prepared from whole-fly brei,Expand
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Mechanism of detoxication of some organophosphorus compounds: the role of glutathione-dependent demethylation.
The detoxication of the geometrical isomers of Bomyl® (dimethyl-1,3-dicarbomethoxy-1-propen-2-yl phosphate) and Phosdrin® (mevinphos, dimethyl-1-carbomethoxy-1-propen-2-yl phosphate) by mouse liverExpand
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Comparative metabolism of two vinyl phosphorothionate isomers (thiono phosdrin) by the mouse and the fly.
Abstract Fly slices activated cis -thiono Phosdrin (mevinphos, dimethyl-l-carbomethoxy-l-propen-2yl phosphorothionate), but this property could not be found in fly homogenates or fly microsomes.Expand
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Differential glutathione-dependent detoxication of two geometrical vinyl organophosphorus (mevinphos) isomers.
Abstract Recent investigations in this laboratory offered an explanation for the different toxicities of the cis and trans isomers of dimethyl-l-carbomethoxy-l-propen-2yl-phosphate, mevinphosExpand
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